Urinary Histology Flashcards
The gross anatomy of the kidney is separated into two groups. What are these groups?
Stroma
Parenchyma
What consists of the kidney stroma?
Non-functional part of kidney, consisting of…
Capsule - dense fibroelastic connective tissue
Fibroblast layer
Peritubular interstitial stroma - loose fibroelastic connective tissue
What is the parenchyma of the kidney?
Functional part of the kidney, consisting of…
nephrons
Collecting duct
Vascular components
What are the functions of the urinary system?
Excrete metabolic waste
Eliminate toxic substances
Modulate blood pressure
Regulate fluid/salt/acid base balance
What are the different types of kidney and in which species are they found?
Unilobulated - dog
Multilobular - ruminants
Intermediate - smooth outer surface, internally interlobular (pig)
What makes up the renal corpuscle?
Glomerulus and Bowman’s capsule
What cells make up the glomerulus?
Podocytes
Mesangial cells
What are mesangials? What do they do? Where do they arise from?
Cells which Interrupt basal lamina
Contain phagocytes
Arise from smooth muscle rather than monocytes
Which is the only tubule in a nephron with a brush border?
PCT
How does the PCT absorb proteins? What border does the PCT have?
Pinocytosis (type of endocytosis)
Brush border
What are the differences between the PCT and DCT?
DCT is shorter
Has no microvilli
What cells line the DCT?
Simple cuboidal cells
Lots of mitochondria - provide ATP for Na reabsorption
What is urothelium?
Transitional epithelium
Type of stratified
What are the 4 layers found in general excretory passages?
Mucosa - lamina propriety, loose fibroelastic CT
Submucosa - merged with lamina propria
Muscularis externa - inner is longitudinal, outer is circular
Adventitia/serosa - loose fibroelastic CT with or without mesothelium
What are the 2 layers of smooth muscle in ureters? Which layer are they in?
Inner longitudinal
Outer circular
Muscularis externa
