drug discovery Flashcards
1
Q
step 1
A
some researcher finding a link between system and enzyme that can be changed to get positive outcome
2
Q
Preclinical development
A
safety pharmacology
-toxicology
-kinetic and dynamic tests
-pharmaceutical development
all done under good laboratory practice (taking shit loads of notes)
3
Q
phase 1
A
small group 20-80 doing safety
4
Q
phase 2
A
100-300 seeing if positive outcome happens
5
Q
phase 3
A
double blind RCT with 1000s of people to find efficacy
6
Q
Phase 4
A
post market tests for long term effect and side effects
