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Flashcards in 2- Myopathies Deck (19)
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1

The aetiology of polymyalgia rheumatica (PMR) is unknown. True/False?

True

2

List clinical features of PMR

Hip and shoulder pain
Morning stiffness lasting longer than 1hr
Improvement with movement/throughout the day

3

Which arteritic condition is associated with PMR?

Giant cell arteritis

4

PMR responds really well to what treatment?

Low-dose steroid (prednisolone)

5

What is the most common form of systemic vasculitis in adults?

Giant cell arteritis

6

List clinical features of GCA

Jaw claudication
Visual disturbance
Headache
Tender scalp
Systemic features

7

What is the definitive test for diagnosing GCA?

Temporal artery biopsy

8

How do polymyositis and dermatomyositis differ?

Essentially the same but dermatomyositis has skin changes

9

Polymyositis is more common in men. True/False?

False
Women 2:1 men

10

Is muscle weakness in polymyositis symmetrical?

Yes

11

List clinical features of polymyositis

Proximal muscle weakness
Myalgia
Difficulty with stairs
Dysphagia (poor prognostic sign)

12

By how much is CK usually raised in polymyositis?

10x

13

Which autoantibodies are associated with polymyositis?

ANA
Anti-Jo-1
Anti-SRP

14

What is the definitive diagnostic test for polymyositis?

Muscle biopsy

15

Outline treatment for polymyositis

Prednisolone 40mg
Immunosuppression

16

List some cutaneous features of dermatomyositis

Heliotrope rash
Gottron's papules
V-shaped rash over chest

17

In which group of people is fibromyalgia most common in?

Young and middle-aged women

18

List clinical features of fibromyalgia

Persistent widespread pain (3+mths)
Fatigue, broken sleep
Cognitive impairment
Depression

19

The mainstay of treatment for fibromyalgia is education and behavioural therapy. What drugs may be given?

Amitryptilline
Gabapentin