3S [LAB]: Drug Abuse Flashcards

(67 cards)

1
Q

Refers to natural alkaloids extracted from poppy

A

Opiates

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2
Q

Opioid are classified as ___, that in moderate doses dull the senses, relieve pain, and induce deep sleep

A

Narcotics

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3
Q

Refers to synthetic opiates and opiate-like drugs

A

Opioids

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4
Q

The most abundant naturally occurring opiate

A

Morphine

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5
Q

Mode of administration of heroin

A

Injection, inhalation

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6
Q

White to dark brown powder or tar-like substance

A

Heroin

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7
Q

Heroin is a ___ form of morphine

A

Diacetyl

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8
Q

A downer or depressant that affects the brain’s pleasure systems and interferes with the brain’s ability to perceive pain

A

Heroin

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9
Q

Heroin overdose is treated with ___

A

Naloxone

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10
Q

Active component of cough syrups because of its antitussive effects

A

Codeine

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11
Q

Mode of administration of codeine

A

Injection, intranasal, smoking

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12
Q

A naturally occurring opiate but can only be synthesized chemically by 3-0-methylation of morphine

A

Codeine

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13
Q

An opiate that has a similar structure to morphine and heroin and acts in a manner similar to that of morphine

A

Codeine

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14
Q

A metabolite of heroin that is used as a powerful analgesic

A

Morphine

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15
Q

Morphine is also known as ___

A

Dilaudid

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16
Q

A minor metabolite of morphine

A

Hydromorphone

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17
Q

Synthetic, nonbicyclic drug that binds competitively with morphine to u-receptors in the brain

A

Methadone

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18
Q

Half-life of methadone in serum

A

20-60 hours

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19
Q

Used as heroin withdrawal therapy

A

Methadone

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20
Q

T/F: D-methadone is used as a potent analgesic

A

False (L-methadone)

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21
Q

T/F: D-methadone is used as an antitussive

A

True

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22
Q

Major cause of drug-related death

A

Propoxyphene (DarVon)

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23
Q

Treatment for propoxyphene (DarVon) overdose

A

Naloxone

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24
Q

An analgesic drug that is 80 times more portent than morphine

A

Fentanyl

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25
A dopaminergic pathway stimulant that is a cocoa plant derivative and is chemically known as benzoylmethylecgonine (INN)
Cocaine
26
Most commonly encountered form of cocaine
HCl (salt)
27
Lower purity form of cocaine that is more affordable
Crack of cocaine
28
Insoluble in H2O but soluble HCl solution form of cocaine
Basic form "freebase"
29
Occasionally seen forms of cocaine
Sulfate (SO4) and Nitrate (NO3)
30
An oral method of administration of cocaine that is wrapped up in rolling paper and then swallowing it
Snow bomb
31
A dopaminergic pathway stimulant that may be administered by rubbing the powder along the gum line or onto cigarette filter then inhaled through smoking
Cocaine (crack)
32
Cocaine hair follicle test can detect the drug within ___ after intake, or may last for a month if hair is uncut
8 hours
33
Cocaine blood test can detect the drug within minutes to as long as ___ after a single dose
5-6 hours
34
Salivary drug test for cocaine can detect the drug after smoking until ___ of its intake
1-2 days
35
Sweat patch drug test for cocaine can detect the drug within ___ after intake
1-4 hours
36
Amphetamine is commonly known as ___
Shabu
37
A dopaminergic pathway stimulant that closely resembles adrenergic amines and dopamine
Amphetamine
38
Unique and rapid thin-layer chromatographic system designed for broad spectrum drug detection and confirmation
Toxi-Lab
39
Tests used to detect amphetamine
Toxi-Lab EMIT
40
A mixture of cut, dried, and ground portions of the hemp plant Cannabis sative
Marijuana (Cannabis)
41
One of the oldest and most widely used of the mind altering drugs
Marijuana (Cannabis)
42
Refers to a more potent product produced by extraction of the resin from the plant
Hashish
43
Half-life of marijuana
1 week
44
Marijuana is detected in the urine within ___
1-4 weeks
45
Marijuana detection should be reported as positive if it has a value of ___
>50 ng/mL
46
Sedative-hypnotics that passes easily across the blood-brain barrier and is used to induce anesthesia or treat epilepsy
Barbiturates
47
T/F: Barbiturates are fat soluble
True
48
Binds to alpha-GABA receptor and increases the duration of chloride ion channel opening
Barbiturates
49
Treatment for barbiturates
Activated charcoal
50
Confirms immunoassay result for sedative-hypnotic barbiturates
TLC
51
3 derivatives of barbiturates
Phenobarbital Pentobarbital Thiopental
52
Also known as angel dust or angel hair
Phencyclidine
53
A hallucinogen that has numerous effects on different neural pathways that is used exclusively as a drug of abuse
Phencyclidine
54
Main mode of administration of Phencyclidine
IV
55
Interact with cholinergic, adrenergic, GABA-secreting, serotonergic, opiate neural receptor
Phencyclidine
56
Block NMDA receptor and binds to specific region in the inner chloride channels of neurons, affecting chloride receptors
Phencyclidine
57
Any non-medical use of drugs that cause physical, psychological, legal, economic, or social damage to the user or to people affected by the user's behavior
Drugs of abuse
58
Screening drug testing laboratories are supervised and operated by a ___
Registered MT and/or chemist
59
Confirmatory drug testing laboratories are supervised and operated by a ___
Registered chemist
60
Tests performed in CDTL
GC-MS and LC-MS
61
Relies on the competition for binding to the antibodies between drug protein conjugates and drugs which may be present in the urine sample
Immunochromatographic dipstick test kit
62
The membrane strip in immunochromatographic dipstick test kit is coated with ___
Drug-protein conjugate
63
The nitrocellulose membrane in immunochromatographic dipstick test kit is conjugated with ___
Antibody-gold
64
Most active component of the psychoactive substance of marijuana
THC
65
Used to treat male hypogonadism and improve muscle mass of athletes
Anabolic steroids
66
Most common sedatives abused
Benzodiazepines & Barbiturates
67