Lecture 4 - Bioinformatics Flashcards Preview

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Flashcards in Lecture 4 - Bioinformatics Deck (6)
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1
Q

In the Blosum-62, what is indicated by a - number when substituting amino acids?

A

Dissimilar substitution (different chemistries)

2
Q

Substitution introduces AA that is similar in size/chemical properties as the substituted AA

A

Conservative

3
Q

Substitution introduces AA that is not similar in size/chemical properties as the substituted AA

A

Non-conservative

4
Q

How many points are awarded for a similar amino acid in the sliding analysis of AAs?

A

+10

5
Q

How many points are added to gaps in sliding analysis of AAs?

A

-10

6
Q

In the Blosum-62, what is indicated by a + number when substituting amino acids?

A

Similar amino acids (regarding chemistry)