Lecture 5 - 3-D Structure of Proteins Flashcards
What is responsible for hydrogen bonding within proteins?
-Amino groups (NH3) -Carbonyl groups (COOH)
The carbons of an AA that lie on either side of the chiral carbon
alpha-Carbon
Alpha-carbons are on same side of the amino acid
Cis
Alpha-carbons on opposite side of the amino acid
Trans
Bond between Nitrogen and chiral carbon
phi
![](https://s3.amazonaws.com/brainscape-prod/system/cm/156/039/696/a_image_thumb.png?1659473407)
Bond between chiral carbon and carboxylic acid group
psi
![](https://s3.amazonaws.com/brainscape-prod/system/cm/156/039/697/a_image_thumb.png?1659473407)
Linear arrangement of AA residues
primary structure
Coiling and/or pleating of amino acid chain
secondary structure
Alpha helices work to stabilize proteins by _____
Hydrogen bonds
Number of amino acids per turn in alpha helix
3.6
In beta strands, when one AA hydrogen bonds with only one other AA, it is a (parallel/anti-parallel).
Anti-parallel
In beta strands, when one AA residue hydrogen bonds to two other AA residues, it is (parallel/anti-parallel)
parallel
Specific 3-D configuration of a peptide chain
Tertiary structure
Bonding between cystiene residues, works to stabilize proteins by covalent linkage
Di-sulfide bonds
The structure of most “structural proteins”
Filamentous (F-proteins)