Pathology Lab: Ischemic Heart Disease

Question 1

The pulmonary artery is _______ to the aorta.

Answer 1

anterior

Question 2

About ____ percent of people supply their posterior heart with their right coronary.

Answer 2

80

Question 3

Lipofuscin are __________.

Answer 3

lysosomal granules indicative of wear

Question 4

Actin filaments attach to ____________.

Answer 4

Z discs (think of Zachtin)

Question 5

CK-MB both peak at __________, but CK-MB returns to normal at ________ and troponin at ___________.

Answer 5

2-4 hours; 72 hours; 7-10 days

Question 6

Differentiate between arteriolosclerosis and atherosclerosis.

Answer 6

Arteriolosclerosis is concentric, primarily in the media, collagenous, and affects the brain, kidneys, eyes, and nerves; atherosclerosis is eccentric, primarily in the intima, lipid, and affects the coronaries, renals, iliacs, andcarotids. Both result from hypertension and diabetes.

Question 7

Following an MI, gross changes will not appear until _______ hours later.

Answer 7

4

Question 8

Following an MI, dark mottling will be present from ___________.

Answer 8

4 hours to 24 hours

Question 9

One to three days following an MI, the tissue will be ___________.

Answer 9

mottled with a yellow-tan center

Question 10

There will be a hyperemic border around yellow-tan infarcted tissue ___________ after an MI.

Answer 10

3-7 days

Question 11

Again, granulation tissue is characterized by ____________.

Answer 11

neovascularization, collagen deposition, and scant macrophages

Question 12

The heart is most liable to rupture ____________.

Answer 12

2-10 days after an MI