Cardiac Embryonic-Fetal Circulation Flashcards

1
Q

The precardiac cells arise from the _____________.

A

middle layer of the mesoderm

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2
Q

_______ migrate through the _________, giving rise to the intraembryonic mesoderm.

A

Epiblast; primitive streak

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3
Q

The heart arises from the __________, an area that is initially the most cephalic structure in the gastrula.

A

cardiogenic area

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4
Q

The cardiogenic area forms __________.

A

two tubes that then get lined with endothelium

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5
Q

By day ________, the primitive heart tube is formed.

A

21-22

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6
Q

Cardiac jelly plays a role in the looping of the heart; it is located between __________.

A

the inner (endothelial) and outer (myocardium and epicardium) layers

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7
Q

During looping of the heart, the atria rotate _____________.

A

posteriorly

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8
Q

Initially, the ventricular outflow tracts are both attached to the ____________.

A

right ventricle

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9
Q

Septation begins at day _________.

A

26-28

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10
Q

The truncus arteriosus becomes the _________.

A

aorta and pumonary artery and semilunar valves

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11
Q

Normally, the heart loops to the ________.

A

right (D-loop)

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12
Q

The bulbus cordus becomes the __________.

A

right ventricle

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13
Q

The primitive ventricle becomes the __________.

A

left ventricle

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14
Q

The atria are derived from the _________.

A

sinus venosus

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15
Q

Blood enters the sinus venosus through three veins: ____________.

A

umbilical vein (blood from the mother), cardinal vein (deoxygenated blood from the fetus), and the vitelline vein (from the yolk sac)

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16
Q

The cardinal vein becomes the ___________.

A

SVC, brachiocephalic veins, and the innominate veins

17
Q

The vitelline veins become the _____________.

A

SMA, IVC, and hepatic sinusoids

18
Q

The umbilical vein becomes ___________.

A

the ductus venosus (which becomes the ligamentum venosum)

19
Q

The great arteries form around day _________.

A

35-56

20
Q

The interventricular septum forms ______________ from ___________.

A

from caudally to cranially; conal crests

21
Q

The ____ aortic arch contributes to the pulmonary arteries and ductus arteriosus.

A

6th

22
Q

The ductus arteriosus functionally closes at __________, but doesn’t anatomically close until _________.

A

12 hours after birth; 2-3 weeks

23
Q

_______ is the prostaglandin responsible for maintaining an open ductus arteriosus.

A

PGE2