Lab: Nephritic/Nephrotic Diseases

Question 1

Comparing nephritic and nephrotic diseases, which typically has higher serum creatinine and BUN?

Answer 1

Nephritic

Question 2

Describe the typical pathological presentation of IgA nephropathy.

Answer 2

Focal mesangial proliferative glomerulopathy

Question 3

What is uremia?

Answer 3

Azotemia with systemic effects

Question 4

Oliguria is typical of which syndrome, nephritic or nephrotic?

Answer 4

Nephritic

Question 5

Histologically, what is HPF?

Answer 5

High-power field

Question 6

Again, what disease often presents as asymptomatic hematuria?

Answer 6

IgA nephropathy

Question 7

Where are immune deposits typically located in IgA nephropathy?

Answer 7

In the mesangium

Question 8

What is Berger disease?

Answer 8

IgA nephropathy

Question 9

What histologic diagnosis will post-infectious GN cause?

Answer 9

Diffuse proliferative glomerulonephritis

Question 10

What is the distinction between focal and diffuse?

Answer 10

50%

Question 11

What histologic diagnosis will Goodpasture’s lead to?

Answer 11

Diffuse crescentic proliferative glomerulonephritis

Question 12

In lupus nephritis, which has a better prognosis, mesangial or subendothelial deposits?

Answer 12

Mesangial