Pathology of Obstructive/Restrictive Lung Disease

Question 1

UIP is worse in the ________ than in the central part of the lungs.

Answer 1

subpleura

Question 2

Which kind of alveolar epithelial cell rapidly divides to replace senescent tissue?

Answer 2

Type II pneumocytes

Question 3

Cardiac output is lower in ____________ (type of COPD).

Answer 3

“pink puffers”

Question 4

Comparing types of COPD, which has better toleration of hypoxia?

Answer 4

Blue bloaters, because bronchitis doesn’t reduce surface area as much as emphysema

Question 5

Elastic recoil is lower in __________.

Answer 5

emphysema

Question 6

What are black dots on the lungs called?

Answer 6

Anthracosis

Question 7

On autopsy, those with hyperinflated lungs will often show ___________.

Answer 7

rib marks on the lungs

Question 8

What is the dividing size for blebs and bullae?

Answer 8

1 cm

Question 9

Fibroblast foci indicate __________ and are ____________.

Answer 9

repair; chronic

Question 10

Macrophages release which cytokines that are associated with ARDS?

Answer 10

IL-1, IL-8, and TNFalpha