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Flashcards in Alcohol Deck (8)
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1

consequences of ethanol metabolism

-decreased NAD+
-increased acetaldehyde-->protein adducts that are immunogenic
-decreased glutathione (GSH)

2

triad of symptoms in fetal alcohol syndrome

retarded body growth, facial abnormalities, and CNS dysfunction

3

drug that reduces urge to drink, mechanism

-naltrexone
-opioid receptor antagonist

4

drug that decreases drinking frequency and reduces relapse

-acamprosate
-GABA mimetic

5

enzyme responsible for ethanol metabolism, coenzyme required, and what it converts ethanol to

alcohol dehydrogenase, NAD+, acetaldehyde

6

enzyme increased in alcoholics that can metabolize ethanol, coenzyme required, and what it converts ethanol to

CYP2E1, NADP+, acetaldehyde

7

enzyme responsible for acetaldehyde metabolism, coenzyme required, and what it converts acetaldehyde to

aldehyde dehydrogenase, NAD+, acetic acid

8

goals of management of acute alcohol intoxication

prevent respiratory depression and aspiration of vomitus