Flashcards in Alcohol Deck (8)
Loading flashcards...
1
consequences of ethanol metabolism
-decreased NAD+
-increased acetaldehyde-->protein adducts that are immunogenic
-decreased glutathione (GSH)
2
triad of symptoms in fetal alcohol syndrome
retarded body growth, facial abnormalities, and CNS dysfunction
3
drug that reduces urge to drink, mechanism
-naltrexone
-opioid receptor antagonist
4
drug that decreases drinking frequency and reduces relapse
-acamprosate
-GABA mimetic
5
enzyme responsible for ethanol metabolism, coenzyme required, and what it converts ethanol to
alcohol dehydrogenase, NAD+, acetaldehyde
6
enzyme increased in alcoholics that can metabolize ethanol, coenzyme required, and what it converts ethanol to
CYP2E1, NADP+, acetaldehyde
7
enzyme responsible for acetaldehyde metabolism, coenzyme required, and what it converts acetaldehyde to
aldehyde dehydrogenase, NAD+, acetic acid
8
