Malignant (usually) in epithelial tissue.
Malignant (usually) for mesenchymal tissues.
Malignant 'tumor' of the lymphoid cells.
Malignant tumor of melanocytes.
Malignant tumor of mesothelium.
Malignant tumor of the testis.
NOT a tumor.
Heterotopic rests of tissue found in another part of the body.
Germ cell tumor from totipotent progenitor. These contain more than one cell type and frequently include teeth, hair, sebaceous secretions, etc.
Mature teratoma is BENIGN
Immature teratoma is MALIGNANT
The lack of differentiation.
This is a hallmark of malignancy. The less differentiated a cell is, the more malignant or advanced that cancer is.
Latency Period of Cancer
Can hang around for a long time. Potentially up to 25 years.
If patients have a previously diagnosed malignancy, no matter what, metastatic disease must ALWAYS be on the differential diagnosis if a new tumor appears.
7 Features of Cancer
1. Suf-sufficiency in growth signals
2. Insensitivity to growth inhibitory signals
3. Evasion of apoptosis
4. Limitless replicative potential
5. Sustained angiogenesis
6. Ability to invade and metastasize
7. DNA repair defects