September 1, 2015 - Antibiotics List Flashcards Preview

COURSE 1 > September 1, 2015 - Antibiotics List > Flashcards

Flashcards in September 1, 2015 - Antibiotics List Deck (15):
1

Penicillin

Class: ß-lactam

Activity: Gram +

MOA: Inhibits cell wall synthesis

2

Aminopenicillin

Class: ß-lactam

Activity: Gram +

MOA: Inhibits cell wall synthesis

 

Eg. ampicillin

3

Cloxacillin

Class: ß-lactam

Activity: Gram +

MOA: Inhibits cell wall synthesis

 

Used against staphylococci that produce beta-lactamase. Due to its large R chain, beta-lactamases cannot bind.

4

Vancomycin

Class: ß-lactam

Activity: Gram +

MOA: Inhibits cell wall synthesis

 

Used particularly against MRSA infections.

5

Cephalosporins

Class: ß-lactam

Activity: Mainly Gram + but later generations also include Gram - 

MOA: Inhibits cell wall synthesis

 

1st generation cephalosporins are highly effective against gram-positive organisms but do not have much effect against gram-negative. As the generations progress, it becomes more and more effective against gram negative.

6

Tetracycline Class

Class: Tetracycline

Activity: Broad Spectrum

MOA: Inhibits protein synthesis

7

Macrolide Class

Class: Macrolides

Activity: Gram + and limited Gram -

MOA: Protein synthesis inhibitor

8

Quinolone Class

Class: Quinolone

Activity: Broad spectrum

MOA: Inhibit DNA Synthesis

 

Eg. Fluoroquinones. Can be used to treat intracellular bacteria.

9

Ciprofloxacin

Class: Quinolone

Target: Broad spectrum

MOA: Inhibits DNA synthesis

10

Clindamycin

Class: Lincosamide

Activity: Aerobic Gram + and Anaerobic Gram -

MOA: Protein synthesis inhibitor

11

Metronidazole

Class: Nitroimidazole

Activity: Broad spectrum anaerobes

MOA: Nucleic acid inhibitor

12

Aztreonam

Class: ß-Lactam

Activity: Gram -

MOA: Inhibits cell wall synthesis

13

Colistin

Class: Polymyxin

Activity: Gram -

MOA: Disrupts cell membrane

14

Aminoglycoside Class

Class: Aminoglycoside

Activity: Gram -

MOA: Protein synthesis inhibitor

15

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