Basal Cell Carcinoma Flashcards Preview

Dermatology - Clinical Medicine IV > Basal Cell Carcinoma > Flashcards

Flashcards in Basal Cell Carcinoma Deck (21)
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1
Q
What does the biopsy look like on BCC?
A
nest of basaloid cells, peripheral palisading, fibromyxoid stroma, cleft formation
2
Q
What is the first step in BCC dx?
A
first do biopsy then if known surgical removal
3
Q
What is the most common skin cancer?
A
BCC
4
Q
Where does BCC arise from?
A
basal layer
5
Q
What is the etiology of BCC?
A
UV radiation induces DNA damage
PTCH (tumor suppressor gene) mutation
6
Q
What are the risk factors for BCC?
A
skin type I and II, severe actinic sun damage, male gender, over 60 yo, immune suppression, genetic condition
7
Q
What is the most common subtype of BCC?
A
nodular
8
Q
Pearly papule or nodule with overlying telangiectasias
A
nodular BCC
9
Q
Where is nodular BCC usually found?
A
head and neck
10
Q
What are features of BCC?
A
translucent color, telangiectasias, central ulceration, rolled boarder, crusting over
11
Q
pink patch and may even having scaling
A
superficial BCC
12
Q
What types of BCC would have pigment?
A
nodular BCC and superficial BCC
13
Q
What are pink or whtite with telangiectasia, plaque and bound down or scar like areas?
A
Morpheaform/infiltrative/sclerotic BCC
14
Q
What does BCC mimic?
A
sebaceous hyperplasia
15
Q
How does sebaceous hyperplasia present?
A
enlarged oil glans, small yellowish papules with central dell, multiple, dermascopy reveals tellangiectasias (not on BCC)
16
Q
What are bnign, small homogenous skin colored to pink papules on nose, no telangiectasias, micmics BCC?
A
fibrous papule
17
Q
What is the surgical tx for BCC?
A
curette and desiccation
cryosurgery
excision with 3-4mm margins
mohs
18
Q
What are the nonsurgical tx for BCC?
A
imiquimod for superficial
5% fluorouracil cream
photodynamic therap
radiation
19
Q
What causes lower recurrance rates?
A
mohs surgery
20
Q
What are the indications for Mohs?
A
location - head or hands
aggressive histologic subtype - sclerosing, morpheaform or micronudlar, large tumors, recurrent tumors
21
Q
What are warning signs of BCC?
A
open sore, reddish patch or irritated area, shiny bump or nodule, pink growth, scar like area