Flashcards in Basal Cell Carcinoma Deck (21)
What does the biopsy look like on BCC?
nest of basaloid cells, peripheral palisading, fibromyxoid stroma, cleft formation
What is the first step in BCC dx?
first do biopsy then if known surgical removal
What is the most common skin cancer?
Where does BCC arise from?
What is the etiology of BCC?
UV radiation induces DNA damage
PTCH (tumor suppressor gene) mutation
What are the risk factors for BCC?
skin type I and II, severe actinic sun damage, male gender, over 60 yo, immune suppression, genetic condition
What is the most common subtype of BCC?
Pearly papule or nodule with overlying telangiectasias
Where is nodular BCC usually found?
head and neck
What are features of BCC?
translucent color, telangiectasias, central ulceration, rolled boarder, crusting over
pink patch and may even having scaling
What types of BCC would have pigment?
nodular BCC and superficial BCC
What are pink or whtite with telangiectasia, plaque and bound down or scar like areas?
What does BCC mimic?
How does sebaceous hyperplasia present?
enlarged oil glans, small yellowish papules with central dell, multiple, dermascopy reveals tellangiectasias (not on BCC)
What are bnign, small homogenous skin colored to pink papules on nose, no telangiectasias, micmics BCC?
What is the surgical tx for BCC?
curette and desiccation
excision with 3-4mm margins
What are the nonsurgical tx for BCC?
imiquimod for superficial
5% fluorouracil cream
What causes lower recurrance rates?
What are the indications for Mohs?
location - head or hands
aggressive histologic subtype - sclerosing, morpheaform or micronudlar, large tumors, recurrent tumors