Basal Cell Carcinoma Flashcards Preview

Dermatology - Clinical Medicine IV > Basal Cell Carcinoma > Flashcards

Flashcards in Basal Cell Carcinoma Deck (21)
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1

What does the biopsy look like on BCC?

nest of basaloid cells, peripheral palisading, fibromyxoid stroma, cleft formation

2

What is the first step in BCC dx?

first do biopsy then if known surgical removal

3

What is the most common skin cancer?

BCC

4

Where does BCC arise from?

basal layer

5

What is the etiology of BCC?

UV radiation induces DNA damage
PTCH (tumor suppressor gene) mutation

6

What are the risk factors for BCC?

skin type I and II, severe actinic sun damage, male gender, over 60 yo, immune suppression, genetic condition

7

What is the most common subtype of BCC?

nodular

8

Pearly papule or nodule with overlying telangiectasias

nodular BCC

9

Where is nodular BCC usually found?

head and neck

10

What are features of BCC?

translucent color, telangiectasias, central ulceration, rolled boarder, crusting over

11

pink patch and may even having scaling

superficial BCC

12

What types of BCC would have pigment?

nodular BCC and superficial BCC

13

What are pink or whtite with telangiectasia, plaque and bound down or scar like areas?

Morpheaform/infiltrative/sclerotic BCC

14

What does BCC mimic?

sebaceous hyperplasia

15

How does sebaceous hyperplasia present?

enlarged oil glans, small yellowish papules with central dell, multiple, dermascopy reveals tellangiectasias (not on BCC)

16

What are bnign, small homogenous skin colored to pink papules on nose, no telangiectasias, micmics BCC?

fibrous papule

17

What is the surgical tx for BCC?

curette and desiccation
cryosurgery
excision with 3-4mm margins
mohs

18

What are the nonsurgical tx for BCC?

imiquimod for superficial
5% fluorouracil cream
photodynamic therap
radiation

19

What causes lower recurrance rates?

mohs surgery

20

What are the indications for Mohs?

location - head or hands
aggressive histologic subtype - sclerosing, morpheaform or micronudlar, large tumors, recurrent tumors

21

What are warning signs of BCC?

open sore, reddish patch or irritated area, shiny bump or nodule, pink growth, scar like area