Melanoma Flashcards
(21 cards)
What is the best way to make a dx of a suspicious pigmented lesion?
excisional biopsy
What age is melanoma most common?
25-29
What is the origin of melanoma?
melanocyte
What is the cause of melanoma?
UVB and UVA exposure - tanning bed
What are risk factors for melanoma?
increasing age, fair skin, blue eyes, blonde, freckling, >25 acquired nevi, atypical nevi, immunosuppression, family history, UV exposure (blistering or indoor tanning)
What is the modifiable risk factor for this?
UV exposure
How does most melanoma develop?
de novo
What is the clinical manifestation of melanoma?
asymptomatic
Where do you see superficial spreading melanoma?
MOST COMMON
back in men, legs in women
horizontal rather than into dermis
What is nodular melanoma?
rapid growth, aggressive, vertical growth
Thickness of primary melanoma measured from the granular layer of epidermis to deepest part of tumor
Breslow’s depth
What is lentigo maligna melanoma?
sun damaged, elderly, slow, horizontal growth
What is acral lentiginous?
darker colored people, dx when lesion large, SOLES OF FEET
What is subungual melanoma?
on great toe or thumb, hx of trauma
When do you refer subungual melanoma?
> 6mm with of dark streak
asymmetric
proximal nail fold
dystrophy of nail
What is amelanotic melanoma?
confusing to dx, recent growth or change helps ddx
What are the ABCDE?
asymmetry, borders, color, diameter, evolving
What do you do when biopsying a pigmented lesion?
ENTIRE LESION
take a photo beforehand
What is the most important prognostic factor for suvival and clinical management?
thickness or depth of tumor invasion
What is used to stage melanoma?
breslow depth
When should melanoma pt follow up?
q 6 mo for 2 years
