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Dermatology - Clinical Medicine IV > Melanoma > Flashcards

Flashcards in Melanoma Deck (21)
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1

What is the best way to make a dx of a suspicious pigmented lesion?

excisional biopsy

2

What age is melanoma most common?

25-29

3

What is the origin of melanoma?

melanocyte

4

What is the cause of melanoma?

UVB and UVA exposure - tanning bed

5

What are risk factors for melanoma?

increasing age, fair skin, blue eyes, blonde, freckling, >25 acquired nevi, atypical nevi, immunosuppression, family history, UV exposure (blistering or indoor tanning)

6

What is the modifiable risk factor for this?

UV exposure

7

How does most melanoma develop?

de novo

8

What is the clinical manifestation of melanoma?

asymptomatic

9

Where do you see superficial spreading melanoma?

MOST COMMON
back in men, legs in women
horizontal rather than into dermis

10

What is nodular melanoma?

rapid growth, aggressive, vertical growth

11

Thickness of primary melanoma measured from the granular layer of epidermis to deepest part of tumor

Breslow's depth

12

What is lentigo maligna melanoma?

sun damaged, elderly, slow, horizontal growth

13

What is acral lentiginous?

darker colored people, dx when lesion large, SOLES OF FEET

14

What is subungual melanoma?

on great toe or thumb, hx of trauma

15

When do you refer subungual melanoma?

>6mm with of dark streak
asymmetric
proximal nail fold
dystrophy of nail

16

What is amelanotic melanoma?

confusing to dx, recent growth or change helps ddx

17

What are the ABCDE?

asymmetry, borders, color, diameter, evolving

18

What do you do when biopsying a pigmented lesion?

ENTIRE LESION
take a photo beforehand

19

What is the most important prognostic factor for suvival and clinical management?

thickness or depth of tumor invasion

20

What is used to stage melanoma?

breslow depth

21

When should melanoma pt follow up?

q 6 mo for 2 years