Flashcards in Melanoma Deck (21)
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1
What is the best way to make a dx of a suspicious pigmented lesion?
excisional biopsy
2
What age is melanoma most common?
25-29
3
What is the origin of melanoma?
melanocyte
4
What is the cause of melanoma?
UVB and UVA exposure - tanning bed
5
What are risk factors for melanoma?
increasing age, fair skin, blue eyes, blonde, freckling, >25 acquired nevi, atypical nevi, immunosuppression, family history, UV exposure (blistering or indoor tanning)
6
What is the modifiable risk factor for this?
UV exposure
7
How does most melanoma develop?
de novo
8
What is the clinical manifestation of melanoma?
asymptomatic
9
Where do you see superficial spreading melanoma?
MOST COMMON
back in men, legs in women
horizontal rather than into dermis
10
What is nodular melanoma?
rapid growth, aggressive, vertical growth
11
Thickness of primary melanoma measured from the granular layer of epidermis to deepest part of tumor
Breslow's depth
12
What is lentigo maligna melanoma?
sun damaged, elderly, slow, horizontal growth
13
What is acral lentiginous?
darker colored people, dx when lesion large, SOLES OF FEET
14
What is subungual melanoma?
on great toe or thumb, hx of trauma
15
When do you refer subungual melanoma?
>6mm with of dark streak
asymmetric
proximal nail fold
dystrophy of nail
16
What is amelanotic melanoma?
confusing to dx, recent growth or change helps ddx
17
What are the ABCDE?
asymmetry, borders, color, diameter, evolving
18
What do you do when biopsying a pigmented lesion?
ENTIRE LESION
take a photo beforehand
19
What is the most important prognostic factor for suvival and clinical management?
thickness or depth of tumor invasion
20
What is used to stage melanoma?
breslow depth
21
