Erythema Multiforme Flashcards Preview

Dermatology - Clinical Medicine IV > Erythema Multiforme > Flashcards

Flashcards in Erythema Multiforme Deck (17)
Loading flashcards...
1

Reaction of blood vessels in dermis

erythema multiforme

2

What type of lesions are in EM?

target, macule papule, vesicles and bullae in center of lesions

3

How does EM develop?

over days

4

How does EM present?

pruritic and painful, bilteral and symmetrical, +/- constitutional symptoms

5

What are the causes of EM?

Infection
Herpes simplex, Mycoplasma
Drugs
Sulfonamides, phenytoin, barbiturates, phenylbutazone, PCN, allopurinol
Idiopathic

6

What sites are affected in EM?

dorsum of hands
PALMS AND SOLES OF FEET
Forearms
Face
Elbows
Knees
Penis
Vulva

7

What mucous membranes of affected?

Lips
Oropharynx
Nasal
Conjunctival
Vulvar
Anal

8

What is EM minor?

HSV
Limited mucous membrane involvement
Classic target lesions
No systemic symptoms
Confined to the extremities and face

9

What is EM major?

Drug reaction
Mucous membrane involvement
Confluent, bullous, erythematous lesions
Systemic symptoms

10

Who gets EM most often?

men

11

Who is at high risk of EM?

HIV +
Bone marrow transplant
SLE
Graft vs host disease
IBD

12

What is the work up for EM?

Generally not needed
Clinical Diagnosis
Severe cases
Blood, sputum, and mucosal cultures

13

What are the supportive tx for EM?

Oral antihistamines
Analgesics
Local skin care
Mouthwashes
Avoid the offending agent
Antiviral- HSV

14

What is EM tx for severe cases?

fluid resuscitation, hospititalization

15

What is EM tx for recurrent cases?

refer to dermatologoy, may need immunosuppressive therapy

16

What is the prognosis with minor?

good, resolves around 1-3 wks

17

What is the prognosis for major?

mortality rate