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Dermatology - Clinical Medicine IV > Terms > Flashcards

Flashcards in Terms Deck (19):
1

What is Intercellular edema in the epidermis signifying inflammation?

Spongiosis

2

What is Mode of keratinization where the nuclei are retained by the stratum corneum- usually related to diseases of increased cell turnover
?

Parakeratosis

3

What is Increased proliferation of granular cells that stick to the epidermis?

Hypergranulation

4

What is Loss of intercellular connections such as desmosomes resulting in keratin cells not being connected to each other?

Acantholysis

5

What is Abnormal development of keratinocytes occurring below the stratum granulosum?

Dyskeratosis

6

What is any object (towels, bedding, etc) capable of carrying infections, such as germs or parasites?

Formites

7

What is Thickening of the stratum corneum due to increased amounts of keratin?

Hyperkeratosis

8

What is The pathway and evolution of keratin cells as they pass from the basal layer to the stratum corneum. Keratinocytes go from being proliferative at the basal layer, to the spinous layer, to the granular layer and lastly to being dead flat cells at the stratum corneum. Most of the keratin related disorders are a result of an imbalance in this balance between proliferation and desquamation?

Epidermal differentiation

9

What is type of scarring on the lower leg that occurs when the blood supply is poor?

Atrophie blanche

10

What is when prolonged repeated stimuli (such as steroids) are used and desensitization occurs bringing about a diminished response

Tachphylaxis

11

What is Softening and breaking down of skin secondary to exposure to moisture for long periods?

Maceration

12

What is an acute rash that develops distant from a primary rash – cause not completely known but thought to be due to immunologic stimuli such as dermatophytes, inflammatory conditions and bacteria- thought to be related to the dissemination of the infectious antigens with secondary immune response?

ID Reaction/Autoezematization

13

What is Group of fungi including Microsporum, Epidermophyton and Trichophyton that can cause infections in the skin, hair and nails- feed off keratin material?

Dermatophytes

14

What is protein produced by the liver in response to inflammation in the body?

C reactive protein

15

What is Naturally occurring photoactive substance taken orally before photo therapy to increase effectiveness of the UV rays?

Oxsoralen

16

What is A dermatitis where the changes occur at the dermis-epidermis junction?

interface dermatitis

17

What is Psoriasis area and severity index - ranges from 0-72 (combines four sections of skin) – includes amount of skin involved + amount of erythema/induration/desquamation?

PASI score

18

What is used in plaque psoriasis to estimate amount of surface of the body that is covered with disease – the size of the palm equals 3%?

BSA - body surface area

19

A characteristic of certain skin diseases in which trauma or irritation of the skin can illicit a primary lesion at that site. Examples: lichen planus, psoriasis.

Koebnerize