Blood Typing Lab

Question 1

ABO typing antigens

Answer 1

• A and B antigens on RBC
• also found in nature
• O means no antigens

Question 2

packed RBC vs whole blood - what is the difference and when is each given

Answer 2

• packed RBC = RBC only and made during centrifugation
• packed RBC given most of. the time
• whole blood = everything, only given during emergency or autologous transfusion (when doing surgery)

Question 3

universal plasma donor

Answer 3

AB since no antibodies in plasma

Question 4

universal plasma receptor

Answer 4

O since no antigens on RBC

Question 5

universal blood donor

Answer 5

O because no antigens on RBC

Question 6

universal blood receptor

Answer 6

AB because no antigens in plasma

Question 7

Rh typing system basic

Answer 7

• positive = present

- negative = absent

Question 8

hemolytic disease of the newborn aka erythroblastosis fetalis symptoms and cause

Answer 8

• low birth weight, jaundice, still born

- anti-Rh antibodies made by mother cross placenta and attack RBC of fetus causing hemolysis

Question 9

series of events leading to HDN

Answer 9

• Rh- women and Rh+ man have Rh+ baby –> during traumatic birth, amniocentesis etc mother exposed to fetal blood and makes Rh antibodies –> antibodies cross placenta and enter fetus

Question 10

HDN prevention and how does it work

Answer 10

• RhoGam = premade Rh antibodies given so that if mother comes in contact with fetal blood no active immunity will be generated (no memory B cells formed)

Question 11

Rh groups during transfusion

Answer 11

Rh- can only get Rh-

Rh+ can get both Rh- and Rh+

Question 12

how are ABO blood types determined

Answer 12

• blood sample placed in anti A and anti B serum

- agglutination means that antigen is present on RBC surface

Question 13

ex: what can AB- receive

Answer 13

• A-, B-, AB-, O-