canale anale Flashcards

1
Q

lesioni premaligne

A

CONDILOMA ACUMINATO

DISPLASIE EPITELIO SQUAMOSO

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2
Q

condiloma acuminato

A

trasmissione sessuale infezione HPV
genotipo basso rischio 6, 11
alto rischio 16, 18

cellule otticamente vuote COLIOCITI solo nucleo
HPV+

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3
Q

displasie epitelio squamoso

A

ASIN - neoplasia anale squamosa intraepiteliale
ASIL - lesione anale squamosa intraepiteliale
AIN - neoplasia anale intraepiteliale

sopra linea dentata
lesioni multicentriche

HIV o condiloma acuminato

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4
Q

CARCINOMA

A

rari, >60y

HPV 16 18
donne
HIV
immunosoppressione
fumo
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5
Q

CARCINOMA

classificazione WHO

A
a. CELLULE SQUAMOSE
.rettale no CK7
.ghiandole perianali
.con fistole anorettali> chron
b. ADENOCARCINOMA
c. MUCINOSO
d. INDIFFERENZIATO
e. NEUROENDOCRINO - APPENDICE
.differenziato
.indifferenziato 
INDICE KI67
f. MIXED ADENO-NEUROENDOCRINE CARCINOMA
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6
Q

CARCINOMA

TNM T

A
Tx 
T0 – nessun evidenza 
Tis – Carcinoma in situ
T1 – <2cm
T2 – >2-5cm
T3 – >5 cm 
T4 – qualsiasi dims invasione organi adiacenti
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7
Q

CARCINOMA

TNM N

A

Nx
N0
N1 linfo perirettali
N2 linfo unilaterali interni iliaci o inguinali
N3 linfo perirettali o inguinali, bilaterali interni iliaci o bilaterali inguinali

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8
Q

CARCINOMA

TNM M

A

M0

M1

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9
Q

MORBO DI PAGET

A

diffusione strutture anatomiche preesistenti di cellule neoplastiche di carcinoma cellule squamose

paget extramammari

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