Flashcards in Cardiovascular Disease and Depression Deck (7)
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1
Q
_____ increases the risk of coronary artery disease
by 1.5-2.0 times in otherwise physically healthy individuals.
A
Depression
2
Q
Depression increases the risk of coronary artery disease
by _____ times in otherwise physically healthy individuals.
A
1.5-2.0
3
Q
What physiologic derangements are assoc with depression?
A
Autonomic dysfunction
Elevated cortisol
Platelet activation
Endothelial dysfunction
Inflammation
4
Q
_____ accounted for a significant portion of the risk of cardiovascular mortality due to depressive symptoms in older adults.
A
Physical inactivity
5
Q
Depressed pts are 2-4x less likely to?
A
- adhere to meds
- follow lifestyle recommendations
- practice self-mgmt.
- receive recommended testing
- FU
6
Q
Depression tx improves which physiologic markers?
A
- Significant decreases in platelet activation markers
- Improved heart rate variability
- Reduced inflammatory markers
- Normalized brain serotonin turnover
7
Q
What are the first line depression txs?
A
- SSRIs
2. Bupropion (Wellbutrin)