Cardiovascular Disease and Depression Flashcards Preview

CVPR exam 2 > Cardiovascular Disease and Depression > Flashcards

Flashcards in Cardiovascular Disease and Depression Deck (7)
Loading flashcards...
1
Q

_____ increases the risk of coronary artery disease

by 1.5-2.0 times in otherwise physically healthy individuals.

A

Depression

2
Q

Depression increases the risk of coronary artery disease

by _____ times in otherwise physically healthy individuals.

A

1.5-2.0

3
Q

What physiologic derangements are assoc with depression?

A

Autonomic dysfunction

Elevated cortisol

Platelet activation

Endothelial dysfunction

Inflammation

4
Q

_____ accounted for a significant portion of the risk of cardiovascular mortality due to depressive symptoms in older adults.

A

Physical inactivity

5
Q

Depressed pts are 2-4x less likely to?

A
  1. adhere to meds
  2. follow lifestyle recommendations
  3. practice self-mgmt.
  4. receive recommended testing
  5. FU
6
Q

Depression tx improves which physiologic markers?

A
  1. Significant decreases in platelet activation markers
  2. Improved heart rate variability
  3. Reduced inflammatory markers
  4. Normalized brain serotonin turnover
7
Q

What are the first line depression txs?

A
  1. SSRIs

2. Bupropion (Wellbutrin)