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Flashcards in Dr. French's Review Sesh Deck (25)
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1

How is LMWH monitored?

monitoring is not needed

2

The fibrinolytic drugs end in -_____.

-teplase

3

How does heparin work?

binds ATIII to inactivate IIa and Xa

3

What is the antidote for Warfarin?

vitamin K

3

_____ is Beta-1 selective.

Metoprolol

3

You would not add a beta-blocker to pts already on ____.

a Ca++ blocker (Verapamil, diltiazem)

4

Metoprolol is _____ selective.

Beta-1

5

How is heparin monitored?

PTT

6

Name 4 drugs a pt will be put on post-MI to improve long term prognosis and why.

1. antiplatelet (reduce thrombosis) 2. ACEI (prevent LV remodeling and endothelial cell dys) 3. statin (reduce LDL, reverse endo cell dys) 4. beta blocker (prevent ischemia, prevent arrhythmias)

8

What do nitrates do to HR?

increase it

10

What drugs relieve ischemic pain?

nitrates and morphine

12

What is protamine?

the antidote for Heparin or LMWH OD

13

Anti-ischemic agents = ?

1. beta blockers  

2. nitrates

14

What drug binds to ATIII to inactivate Xa?

LMWH

15

What is the difference btw unstable angina and NSTEMI?

the presence of serum biomarkers = NSTEMI

16

When would you decide to give a Ca++ blocker if the goal was to decrease myocardial O2 demand?

the pt cannot tolerate Beta-blockers

17

Verapamil and diltiazem work by _____.

blocking the L-type Ca++ channel (phase 0 in nodal cells, phase 2 in cardiomyocyte)

18

What are the 3 categories of antiplatelet agents? Examples?

1. COX1 inhibitors (low dose aspirin) 2. ADP/P2Y12 inhibitors (clopidogrel/Plavix) 3. GIIb/IIIa inhibitors (eptifibatide, tirofiban, abciximab) *** IV only

19

What is an example of a direct thrombin (IIa) inhibitor?

dabigatran

20

Beta-blockers are not direct _____.

vasodilators

21

How does tPA work?

it activates plasminogen to plasmin, and plasmin lyses the clot

22

What are the contraindications for beta-blockers?

1. excess bradycardia 2. severe heart block 3. Prinzmetal's angina 4. asthma 5. concurrent Ca++ blockers

23

How do statins work?

decrease LDL = prevent infiltration that leads to atherosclerosis

24

How does LMWH work?

binds to ATIII to inactivate Xa

25

What is the antidote for Heparin or LMWH OD?

protamine