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Flashcards in Dr. French's Review Sesh Deck (25)
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1
Q

How is LMWH monitored?

A

monitoring is not needed

2
Q

The fibrinolytic drugs end in -_____.

A

-teplase

3
Q

How does heparin work?

A

binds ATIII to inactivate IIa and Xa

3
Q

What is the antidote for Warfarin?

A

vitamin K

3
Q

_____ is Beta-1 selective.

A

Metoprolol

3
Q

You would not add a beta-blocker to pts already on ____.

A

a Ca++ blocker (Verapamil, diltiazem)

4
Q

Metoprolol is _____ selective.

A

Beta-1

5
Q

How is heparin monitored?

A

PTT

6
Q

Name 4 drugs a pt will be put on post-MI to improve long term prognosis and why.

A
  1. antiplatelet (reduce thrombosis) 2. ACEI (prevent LV remodeling and endothelial cell dys) 3. statin (reduce LDL, reverse endo cell dys) 4. beta blocker (prevent ischemia, prevent arrhythmias)
8
Q

What do nitrates do to HR?

A

increase it

10
Q

What drugs relieve ischemic pain?

A

nitrates and morphine

12
Q

What is protamine?

A

the antidote for Heparin or LMWH OD

13
Q

Anti-ischemic agents = ?

A
  1. beta blockers
  2. nitrates
14
Q

What drug binds to ATIII to inactivate Xa?

A

LMWH

15
Q

What is the difference btw unstable angina and NSTEMI?

A

the presence of serum biomarkers = NSTEMI

16
Q

When would you decide to give a Ca++ blocker if the goal was to decrease myocardial O2 demand?

A

the pt cannot tolerate Beta-blockers

17
Q

Verapamil and diltiazem work by _____.

A

blocking the L-type Ca++ channel (phase 0 in nodal cells, phase 2 in cardiomyocyte)

18
Q

What are the 3 categories of antiplatelet agents? Examples?

A
  1. COX1 inhibitors (low dose aspirin) 2. ADP/P2Y12 inhibitors (clopidogrel/Plavix) 3. GIIb/IIIa inhibitors (eptifibatide, tirofiban, abciximab) *** IV only
19
Q

What is an example of a direct thrombin (IIa) inhibitor?

A

dabigatran

20
Q

Beta-blockers are not direct _____.

A

vasodilators

21
Q

How does tPA work?

A

it activates plasminogen to plasmin, and plasmin lyses the clot

22
Q

What are the contraindications for beta-blockers?

A
  1. excess bradycardia 2. severe heart block 3. Prinzmetal’s angina 4. asthma 5. concurrent Ca++ blockers
23
Q

How do statins work?

A

decrease LDL = prevent infiltration that leads to atherosclerosis

24
Q

How does LMWH work?

A

binds to ATIII to inactivate Xa

25
Q

What is the antidote for Heparin or LMWH OD?

A

protamine