Ch3 Laboratory findings in inflammation EC Flashcards Preview

Evan's Step 1 Prep Material > Ch3 Laboratory findings in inflammation EC > Flashcards

Flashcards in Ch3 Laboratory findings in inflammation EC Deck (10):
1

Neutrophilic leukocytosis

Cytokine release of postmitotic neutrophils from bone marrow

2

Left-shifted smear

Increase band PMNs (>10%) in peripheral blood

3

Toxic granulation

Dark blue/purple primary granules in PMNs
Due to abnormality in maturation of granules

4

Dohle bodies

Gray-blue inclusions in PMNs
Accompanies toxic granulation

5

Lab findings in chronic inflammation

Monocytosis and increased IgG

6

Corticosteroids effect in blood:

Increased PMNs (inhibit integrins)
Decreased lymphocytes (induce apoptosis)

7

ESR

Rate of settling of RBCs
Increased with plasma factors (rouleau formation)

8

C-Reactive Protein (CRP)

Marker of necrosis and disease activity

9

Serum protein electrophoresis in acute inflammation

Decreased albumin (due to increased synthesis of acute phase reactants)
No alteration in gamma-globulin peak

10

Serum protein electrophoresis in chronic inflammation

Decreased albumin
Polyclonal gammopathy due to increased synthesis of IgG

Decks in Evan's Step 1 Prep Material Class (72):