Rate-Determining Enzymes EC Flashcards Preview

Evan's Step 1 Prep Material > Rate-Determining Enzymes EC > Flashcards

Flashcards in Rate-Determining Enzymes EC Deck (13):
1

Glycolysis rate-determining enzyme and regulators

PFK-1 (phosphofructokinase-1)

+ AMP, fructose 2,6BP
- ATP, citrate

2

Gluconeogenesis rate-determining enzyme and regulators

Fructose-1,6-bisphosphatatse

+ ATP,
- AMP, fructose 2,6BP

3

TCA cycle rate-determining enzyme and regulators

Isocitrate dehydrogenase

+ ADP
- ATP, NADH

4

Glycogen synthesis rate-determining enzyme and regulators

Glycogen synthase

+ Glucose, Insulin
- Epinephrine, Glucagon

5

Glycogenolysis rate-determining enzyme and regulators

Glycogen phosphorylase

+ AMP, Epinephrine, Glucagon
- Insulin, ATP

6

HMP shunt rate-determining enzyme and regulators

G6PD (glucose-6-phosphate dehydrogenase)

+ NADP
- NADPH

7

De novo pyrimidine synthesis rate-determining enzyme and regulators

CMP-II (Carbamoyl phosphate synthetase II)

8

De novo purine synthesis rate-determining enzyme and regulators

Glutamine-PRPP aminotransferase

- AMO, IMP, GMP

9

Urea cycle rate-determining enzyme and regulators

Carbamoyl phosphate synthetase I

+ N-acetylglutamate

10

Fatty acid synthesis rate-determining enzyme and regulators

ACC (Acetyl-CoA Carboxylase)

+ Insulin, Citrate
- Glucagon, palmitoyl-CoA

11

Fatty acid oxidation rate-determining enzyme and regulators

Carnitine acyltransferase I

- Malonyl-CoA

12

Ketogenesis rate-determining enzyme and regulators

HMG-CoA synthase

13

Cholesterol synthesis rate-determining enzyme and regulators

HMG-CoA reductase

+ Insulin, Thyroxine
- Glucagon, Cholesterol

Decks in Evan's Step 1 Prep Material Class (72):