Chpt 13 (14) - Lymph & Immune System Flashcards

(64 cards)

1
Q

Lymphatic System: Functions

A
  • Reduces tissue edema (swelling)
  • Returns proteins from interstitial fluid back to blood
  • Traps and Filters cellular debris and foreign substance; bacteria, toxins, cancer cells, viruses, pathogens
  • Recycles body fluid
  • Circulates lymphocytes to assist with immune function
  • Transports fats from GI tract back to blood stream
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2
Q

Immune System: Functions

A
  • Protects the body from foreign invasion
  • Coordinates activities in the blood stream, tissues, and lymph to protect body from invasion
  • Fights infection and protects against future infections by producing antibodies and immune cells
  • Production of immunoglobulin (Antibodies)
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3
Q

Lymphatic System

A

1 way “drainage” of tissue plasma back to heart to lower edema (swelling) of body’s tissue

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4
Q

Afferent Lymphatic Vessels

A

Bring fluid into lymph nodes

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5
Q

Efferent Lymphatic Vessels

A

Allow fluid to leave lymph nodes

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6
Q

Germinal Centers (follicle)

A

“Filter” sites within lymph nodes which contain macrophages to filter fluid

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7
Q

Hilus

A

Area of lymph node where efferent vessels exit

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8
Q

Medulla

A

Center of lymph node

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9
Q

Capsule

A

Outer shell of lymph node

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10
Q

Papilteal

A

Region around knee containing lymph nodes

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11
Q

Inguinal and Femoral

A

Region around groin and femur point which contains lymph nodes

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12
Q

Mesenteric

A

RLQ, above Inguinal which contains lymph nodes

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13
Q

Spleenic

A

LUQ, spleen as a lymph node

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14
Q

Mediastinal

A

Region in middle of chest which contains lymph nodes

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15
Q

Axillary

A

Region near armpits which contain lymph nodes

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16
Q

Infraclavicular

A

Region near clavicle which contains lymph nodes

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17
Q

Cervical

A

Region around throat which contains lymph nodes

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18
Q

Hilar

A

Region near heart that contains lymph nodes

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19
Q

Lymph Pathways

A

Vessels that transport lymph fluid

 - Lymph capillaries
 - Receive fluid and debris 
 - Moves one way, toward heart
 - Valves encourage one way flow
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20
Q

Lymph Nodes

A
  • Located near joints
  • Filter foreign substances
  • Primary Filtering agents:
    • Macrophages
    • Lymphocytes

No lymph nodes in CNS

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21
Q

Spleen

A
  • Largest lymph organ
  • LUQ of abdomen
  • Removes: Bacteria, Old RBCs
  • Filters Blood
  • Produces antibodies
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22
Q

Cells of Immune System

A

Stem Cells produce:

 - Lymphoid 
 - Myeloid 
  • Lymphoid produce:
    • Lymphocytes
      • B Cells
      • T Cells
  • Myeloid produce:
    • Granulocytes
      • Neutrophils
      • Eosinophils
      • Basophils
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23
Q

Lymph and Immune Systems

A
  • Share same structure and function roles
  • Both Contain:
    • Spleen
    • Lymph Nodes
    • Thymus
    • Immune Cells (Leukocytes)
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24
Q

B Cells

A

Secrete Antibodies

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25
Cytotoxic T Cells
Engulf and kill cancer and infected cells
26
Helper T Cells (T4)
Activate B Cells and Cytotoxic T Cells - Affected by HIV
27
From Leukocytes
Neutrophils - Phagocytes Basophils - Inflammation Eosinophils - Parasite Infection Lymphocytes - Specific Immune Response
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Neutrophils
Engulf bacteria and cellular debris; Frontline of immunity - Myeloid
29
Lymphocytes
Produce Antibodies and regulate immune response (B & T Cells) - Specific Immunity
30
Monocytes
Associated with engulfing cellular debris, antigen processing
31
Eosinophils
Associated with parasitic infection and allergic response | - Myeloid
32
Basophils
Associated with hypersensitivity and release histamine
33
Helper T Cells
Used to activate B Cells to release antibodies to go fight pathogen
34
Defense Against Pathogen
Pathogen: Disease producing agent Mechanical & Chemical Defenses: - Skin; Mucus Membranes, Cilia - Gastric Juices Natural Immunity: - Natural resistance to certain disease Acquired Immunity: - Exposure to pathogen or vaccination - Humoral and Cell Mediated
35
Humoral Immunity
B cells which become plasma cells: - Secrete immunoglobulin (antibodies) - IgG: Bacteria, virus, toxins activate this antibody - IgA: In breast milk, tears, nasal fluid, saliva, gastric juice - IgM: Bacteria, virus' activate this antibody first - IgE: Important in Allergic Reaction
36
Cell Mediated Immunity (T Cells)
- Acquired active immunity: by T Cell action - T Cells specific to antigen - Reproduce and secrete cytokines / lymphokines - T Cells also activate B cells which secrete antibodies - Helper T Cells: T4 that stimulate immune response - Cytotoxic T Cells: T8 destroy infected cells
37
Aden (o)
Gland
38
Immun (o)
Immunity
39
Lymph (o)
Lymph
40
Lymphaden (o)
Lymph Nodes
41
Lymphangi (o)
Lymphatic Vessels
42
Splen (o)
Spleen
43
Thym (o)
Thymus
44
Tox (o); Toxic (o); Toxi
Poison
45
ALL
Acute Lymphocytic Leukemia
46
AML
Acute Myelogenous Leukemia
47
CLL
Chronic Lymphocytic Leukemia
48
CML
Chronic Myelogenous Leukemia
49
CMV
Cytomegalo Virus
50
PCP
Pneumocystis Carinii Pneumonia
51
* EBV *
Epstein-Barr Virus
52
HSV
Herpes Simplex Virus
53
Hodgkin's Lymphoma
Lymph cancer usually appears in early adulthood
54
Non-Hodgkin's
Lymph cancer with some healthy cells and spreading in diffusive pattern; appears in middle or older age
55
Hypersplenism
Overactive enlarged spleen
56
Anaphylaxis
Life-threatening allergic reaction
57
Mononucleosis
EBV infection
58
Splenomegaly
Enlarged spleen
59
Thymoma
Tumor of thymus gland
60
Sarcoidosis
Inflammatory condition with lesions involving the lymph nodes, lungs, and other organs
61
Lymphadenectomy
Removal of lymph node
62
Lymphadenotomy
Incision into a lymph node
63
Splenectomy
Removal of spleen
64
Thymectomy
Removal of thymus gland