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Flashcards in Development of the Urinary System Deck (33):
1

both the urinary and genital systems (urogenital system) develop from common ____ known as ____

mesodermal ridge; intermediate mesoderm

2

intermediate mesoderm bulges into intraembryonic coelmic cavity creating the _____

urogenital ridge

3

the urogenital ridge differentiates into:

-nephrogenic cord/ridge (lateral)
-genital ridge (medial)

4

through lateral folding, the nephrogenic cord becomes ____

retroperitoneal

5

three slightly overlapping kidney systems develop in ____ to ____ sequence

cranial; caudal

6

three kidney systems

1. Pronephros (rudimentary, nonfunctional)
2. Mesonephros (function for a short time during early fetal period)
3. Metanephros (forms the permanent kidney)

7

pronephros appear early ____ and degenerate by the end of this week

week 4

8

pronephros in segmented _____ in the ____ region; never functional in humans

intermediate mesoderm; cervical

9

mesonephros appear early week ___ in ___ and ____ segments of intermediate mesoderm

4; thoracic/lumbar

10

in the mesonephros, urine is produced and drains along the _____ to the ____

mesonephric (Wolffian) duct; cloaca/bladder

11

in week 5, the ___ segments of the mesonephros start to regress, but the mesonephric kidney continues functioning until week ___

thoracic; 10

12

mesonephric ducts extend into lower lumbar and fuse with ____, contributing to _____

cloaca; posterior bladder

13

in the mesonephros, canalization begins ____ and grows ____

caudally; cranially

14

when the mesonephric duct hits the cloaca, it initiates _____ growth

ureteric bud/metanephric diverticulum

15

metanephros begins when the ____ sprouts from the distal end of the _____ at about 5 weeks

ureteric bud/metanephric diverticulum; mesonephric duct

16

formation of the metanephros induces intermediate mesoderm in the sacral region to form a ____ which forms the _____

metanephric blastema which forms the glomeruli and tubules of the nephrons

17

2 components of metanephros

-collecting portion (ureteric bud)
-excretory portion (metanephric blastema)

18

close proximity of blastema to ureteric bud is needed to induce nephron differentiation; if bud is missing or abnormal, kidney will not develop

reciprocal induction

19

collecting portion of metanephros that comes from ureteric bud

-ureter
-renal pelvis
-major and minor calyces

20

excretory portion of metanephros coming from metanephric blastema

-Bowman's capsule
-proximal convoluted tubule
-Loop of Henle
-distal convoluted tubule

21

ascent of the kidneys involves ____; vascular buds grow toward _____ arteries; happens approximately weeks ____

vasculogenesis; common iliac; 6-9

22

ascent of the kidneys continues until they hit the ____ at about ____ vertebral level

adrenal glands; T11-T12

23

when a kidney does not ascend and remains in the pelvis; can be functional but sometimes are not; has a very short ureter

pelvic kidney

24

when the 2 inferior poles of the kidneys fuse together and get stuck on IMA (L3 level) as they ascend

horseshoe kidney

25

in developing the bladder, the cloaca in the hindgut becomes divided by the ____

urorectal septum

26

urorectal septum divides the cloaca into what 2 portions

ventral urogenital sinus and dorsal anorectal canal

27

superior part of the urogenital sinus that is connected to the allantois and will form the bulk of the bladder

the vesical part

28

middle and inferior portions of the urogenital sinus that will form the urethra

pelvic and phallic parts

29

the distal portions of the mesonephric ducts and the attached ureteric ducts become incorporated into the posterior aspect of the bladder, known as the ____ of the bladder

trigone

30

the mesonephric ducts will become the ____ in males, and the ureteric ducts will become the ____

vas deferens; ureters

31

the mesonephric and ureteric ducts somewhat criss cross with the ____ over top of the ____

mesonephric duct; ureteric duct

32

in females, the ___ and part of the ____ develop from the pelvic part of the urogenital sinus

whole urethra; vagina

33

in males, the ___ and ____ parts of the urethra develop from the pelvic portion of the urogenital sinus, and the ____ comes from the phallic part

prostatic and membranous from pelvis part
spongy urethra from phallic part