Diagnostic Approach To Neutopenia

Question 1

Diagnostic approach to neutropenia

Answer 1

1-confirm neutropenia:
*Mild: 1000–1500 /μL
*Moderate: 500–1000 /μL
*Severe: <500 /μL
2-History and Physical Examination
Important points:
Recent infections, medications, autoimmune symptoms
3-causes
Infections:
*Viral: CMV,EBV,HIV
*Bacterial infection:TB *.Malaria
* SLE
* Bone marrow failure:
أسباب نخاعية
* Any B.M. infiltration.
* Leukemic leukemia
* Myelodysplastic leukemia
* Multiple myeloma
* Cytotoxic drugs
* Sulpha
* Hypersplenism