Q Fever

Question 1

المفتاح

Answer 1

Q fever
حرف ك…
Q feve جاي من cow بسبب coxellia
* Chronic q fever=endocarditis+encephalitis+كلي
Acute..fever, pneumonia,كبد
*Diagnosis…indirect immunofluorescent..pcr..elisa
*Ttt..برضه حرف ك
دوك + كينولون +هيدروكسيكلوروكين
doxy 100 mg 1214
,quinolonesك
+
If chronic…hydroxychloroquine+doxy for 1.5-4years or for life
*Vaccine=q vax

Question 2

Causative organism

Answer 2

Coxiella burnetii

Question 3

Mode of transmission

Answer 3

Cow كلمة السر
*Cattle, sheep & goats are important reservoirs of the organism.
* Ingestion of raw milk or milk products of animals.
* Inhalation of aerosols.

Question 4

C/p

Answer 4

1-Acute:
Fever
* Pneumonia
* Hepatitis
* ↑ ALT, AST
2- Chronic Q fever →ك *endocarditis (“Negative culture endocarditis”)
*Encephalitis
*Kidney impairment

Question 5

Diagnosis

Answer 5

1-Indirect immunofluorescent (The method of choice)
* PCR
* Antibody detection

Question 6

Treatment

Answer 6

*Doxycycline 100mg IV/PO x 14 days
Fluoroquinolones may also be helpful.
*In chronic cases → Hydroxychloroquine + Doxycycline for 1.5 - 4 years or for life.

Question 7

Vaccine

Answer 7

من اسمه Q vax
مين ياخده؟
Given only for people no Hx of Q-fever
+ Negative seology $skin test.

Question 8

Coxiella burnetii is a Rickettsia-like organism

Answer 8

ايه الفرق بينهم
Coxiella burnetii is :
* Doesn’t cause rash
* Highly resistant to heat & disinfection

Question 9

The followings are the symptoms of acute Q fever EXCEPT?
A. Meningoencephalitis is a common symptom.
B. It presents as a flu-like febrile illness.
C. Q fever presents typical pneumonia.
D. Q fever hepatitis is a common symptom.

Answer 9

A
ده بتاع chronic