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Flashcards in Hemolytic anemia Deck (11)
1

what are the haptoglobin levels in hemolytic anemia? why?

1. decreased
2. taking away all the Hb

2

what are the LDH levels in hemolytic anemia? why?

1. elevated
2. RBC breakdown

3

what are the reticulocyte levels in hemolytic anemia? why?

1. elevated
2. hyperproliferative bone marrow

4

what is the result of a Coomb's test in hemolytic anemia? why?

1. positive
2. Ab or complement mediated hemolysis

5

what are the indirect bilirubin levels in hemolytic anemia? why?

1. elevated
2. RBC breakdown

6

what are the urine hemosiderin levels in hemolytic anemia? why?

1. high
2. intravascular hemolysis

7

what is the most common enzymatic disorder of hemolytic anemia? what is the inheritance?

1. G6PD
2. x linked

8

heinz bodies and bite cells are seen with what condition?

G6PD deficiency hemolytic anemia

9

what is the pathogenesis of sickle cell anemia?

1. mutation in B globin gene
2. both B globin genes affected
3. deoxygenated Hb S stiffens RBC membrane

10

patient who have sickle cell anemia are prone to what type of organisms?

encapsulated and salmonella

11

what are the drug associated hemolysis?

penicillins, quinine, methyldopa, certain cephalosporin abx