Radiation oncology Flashcards Preview

Year 2 Hematology > Radiation oncology > Flashcards

Flashcards in Radiation oncology Deck (26)
1

what are the top 3 cancer cases for men in the US?

1. prostate
2. lung
3. colon and rectum

2

what are the top 3 cancer cases for women in the US?

1. breast
2. lung
3. colon and rectum

3

what are the top 3 cancer deaths for men in the US?

1. lung
2. prostate
3. colorectal

4

what are the top 3 cancer deaths for women in the US?

1. lung
2. breast
3. colorectal

5

what is the staging for lymph node mets?

N

6

what is the staging for hematogenous mets?

M

7

what is the staging for adjacent organ tumor invasion?

T3-4

8

what is the role of radiation in tumor treatment?

to replace or complement surgery

9

what particle is used for deep seated tumors?

photons (x rays)

10

what particle is used for superficial tumors?

electrons

11

definition: radiosensitive

tumor melts with RT - does not depend on kinetics

12

definition: radioresponsive

tumor melts quickly

13

what are classic examples of tumors that are both radiosensitive and radioresponsive?

lymphoma, small cell lung

14

what is the main target for radiation therapy? what is the most important lesion produced?

1. DNA of well oxygenated tumors in M/G2 phase
2. double strand DNA break

15

what is the radiosensitive phase of a tumor?

M/G2

16

what is the radioresponsive phase of a tumor?

S

17

what biological process is essential to radiation cell kill over time?

reoxygenation

18

GTV

gross tumor volume - seen with naked eye

19

CTV

1. margin on GTV to account for tissue with presumed tumor / typical site of disease spread
2. assumes no tumor cells outside this volume

20

ITV

CTV plus internal margin for physiological movements / error

21

PTV

CTV or ITV plus setup margin uncertainty / error

22

what is IGRT?

a way to verify with greater precision the tumor's position to allow for more accurate treatment

23

what are the indications for IGRT?

1. tumors that move
2. tumors abutting critical structures such as spinal cord and brainstem

24

what are the two types of IGRT?

1. stereoscopic / bony
2. cone beam / soft tissue

25

what is stereoscopic / bony IGRT?

uses bone structure as template for alignment

26

what is cone beam / soft tissue IGRT?

uses a same-day CT for fusion to simulation image