Herpesvirus infections Flashcards
(10 cards)
Which HSV serotype mainly causes oral and lip infections?
HSV-1.
Which HSV serotype is most commonly associated with genital herpes?
HSV-2 (but HSV-1 can also cause genital infection).
Are topical antivirals routinely recommended for uncomplicated oral HSV infections in immunocompetent individuals?
No, they are generally not recommended.
What symptomatic treatments are recommended for oral HSV infections?
Oral paracetamol, topical anaesthetics, and mouthwashes.
When should oral antiviral treatment be considered for oral HSV infections?
In severe, frequent, or persistent oral infections.
What is the first-line oral antiviral treatment for first episode genital herpes?
Aciclovir 400 mg three times daily for 5 days, or valaciclovir 500 mg twice daily for 5 days.
Why is ibuprofen not recommended in children with chickenpox?
It increases the risk of severe skin and soft tissue infections like necrotizing fasciitis and may worsen symptoms.
What virus causes shingles (herpes zoster)?
Reactivation of varicella-zoster virus (VZV).
What is post-herpetic neuralgia?
Chronic pain that persists after the shingles rash has healed.
What post-exposure prophylaxis options exist for varicella-zoster virus?
Oral or IV aciclovir or valaciclovir, and varicella-zoster immunoglobulin (VZIG) for some high-risk neonates.
