Infection in immunocompromised host

Question 1

Possible infections in burns victims

Answer 1

pseudomonas or group A strep

Question 2

Possible infection when neutrophils not working properly (qualitative)

Answer 2

Staph aureus

Question 3

Dangerous infection in neutropenic patients

Answer 3

Pseudomonal

Question 4

Possible infections in neutropenic patients

Answer 4

Gram negative bacilli, gram positive cocci

Candida, aspergillus ssp.

Question 5

Treatment for neutropenic patients infected

Answer 5

Abx- aminoglycoside + antipseudomonal penicillin +/- gentamicin

Question 6

Possible infections in T cell deficiencies

Answer 6

Listeria monocytogenes, mycobacteria
HSV, CMV, VZV
Candida ssp, cryptococcus ssp
Cryptosporidium parvum, Toxoplasma gondii, Strongyloides stercoralis (nematode, may have gram -ve septicaemia- tropical countries/exPOW)

Question 7

Possible infections in hypogammaglobulinaemic patients

Answer 7

S. pneumoniae
Giardia lamblia
Cryptosporidium

Question 8

Possible infections in complement deficient

Answer 8

Depends on which complement C5-8 neisseria meningitidis.

Frequent, serious Strep pneumoniae

Question 9

Possible infections in splenectomy

Answer 9

Strep. pneumoniae
haemophilus influenzae type B
N. meningitidis
malaria

Question 10

Possible infections in ‘biologic’/ antibody or other peptide deficiency

Answer 10

TB
HZV
legionella pneumophilia
listeria monocytogenes

Question 11

Possible infections in organ transplant early on

Answer 11

CMV, aspergillus

Question 12

Possible infections in organ transplant later

Answer 12

zoster, listeria

Question 13

Treatment for hypogammaglob. patients with infection

Answer 13

Ig replacement

Question 14

Treatment for splenectomy

Answer 14

vaccination, prophylactic penicillin, education (seek help if unwell)