Bacterial and fungal encephalitis Flashcards Preview

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Flashcards in Bacterial and fungal encephalitis Deck (25):
1

Difference in presentation between encephalitis and brain abscess?

Brain abscess has insidious onset of meningism (acute onset in encephalitis)

2

Cell count difference in blood results in bacterial, viral TB and cryptococcal meningitis

Bac- >200
all others 20-200

3

cell type difference in blood results in bacterial, viral TB and cryptococcal meningitis

Bacterial has polymorphs, rest lymphocytes

4

Glucose difference in blood results in bacterial, viral TB and cryptococcal meningitis

Reduced in all, but viral and cryptococcus could be normal

5

protein difference in blood results in bacterial, viral TB and cryptococcal meningitis

All increased, but viral could be normal

6

Neisseria meningitidis is normal flora where?

Nasopharynx

7

2 things neisseria meningitidis can cause

Meningitis and septicaemia in various forms

8

Rx of neisseria meningitidis?

Ceftriaxons and cefotaxime
Penicillin

9

Chemoprophylaxis for contact for all forms of bacterial meningitis except? What would the treatment be in the others?

Strep pneumoniae
Rifampicin

10

Vaccinations are available against which strains of neisseria meningitidis?

A, B, C, W135

11

Which type of haemophilus influenza causes the most invasive disease?

B

12

Rx haemophilus influenza?

Ceftriaxons and cefotaxime
Ampicillin

13

Which type of bacterial meningitis is more common and severe in the elderly?

Strep. pneumoniae

14

Rx strep pneumoniae?

Ceftriaxons and cefotaxime
(Penicillin resistant is common in some areas)

15

What is raised in CSF in bacterial meningitis?

Neutrophils

16

What is a treatment for streptococcal meningitis other than antibiotics?

Steroids- dexamethasone

17

Interaction of dexamethasone?

Vancomycin- decreases levels in CSF so must also give rifampicin

18

3 causative agents of bacterial meningitis?

Neisseria meningitidis
Haemophilus influenzae
Streptococcus pneumoniae

19

3 causes of neonatal meningitis?

Group B beta haemolytic streptococci
E coli
Listeria monocytogenes

20

Rx neonatal meningitis

cefotaxime
ampicillin and gentamicin

21

Complications of meningitis (8)

Death
Sepsis
Raised ICP
Deafness
Delayed development
Seizures
Stroke
Hydrocephalus

22

Are brain abscesses normally bacterial or viral?

Bacterial

23

What is needed to confirm Dx of brain abscess?

Brain imaging

24

Rx brain abscess?

Prolonged antibiotics
Drainage

25

Rx cryptococcal meningitis?

amphotericin, flucytosine or fluconazole