INHIBITORS OF COAGULATION Flashcards

1
Q

what are the inhibitors of coagulation?

A

antithrombin III
protein C
protein S

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2
Q

antithrombin activated by?

A

heparin

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3
Q

antithrombin III deficiency results in?

A

venous thrombosis, can be hereditary or acquired

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4
Q

protein C is activated by?

A

thrombomodulin

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5
Q

protein C action?

A

increases production of t-PA (tissue plasminogen activator)

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6
Q

protein C deficiency results in?

A

increased risk of thrombosis(prothrombotic)

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7
Q

protein S fxn?

A

used for protein C to read max effect

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8
Q

protein S deficiency results in?

A

increased risk of thrombosis

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9
Q

fibrinolytic system uses?

A

Plasminogen-Plasmin

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