ISCHEMIC HEART DISEASE

Question 1

myocardium suffers from oxygen deficiency due to this?

increase in demand
decreased O2 transport in blood
reduced coronary blood flow (90%) due to atherosclerotic CAD

Answer 1

ischemic heart disease

Question 2

clinical manifestations of ischemic heart disease?

Answer 2

angina pectoris

myocardial infarction

Question 3

this type of ischemic is less severe and does not cause death of cardiac muscle

Answer 3

angina pectoris

Question 4

what are the types of intermittent chest pain, characteristic of angina pectoris?

Answer 4

typical(stable) most common
prinzmetal (variant)
unstable (crescendo)

Question 5

this is severe ischemia with death of cardiac muscle, leading causes of death in US?

types

Answer 5

myocardial infarction

subendocardial
transmural

Question 6

gross morphology?
<6-12 hours
2-3 hours
18-24 hours
7 days
6 weeks

Answer 6

nothing

brick red color, infarct=pale
zone, scar=white and glistening

pallor

sharp definition

well developed scar

Question 7

histology?
<4-8
4-12
18-24
24-72
3-10 days
2-4 weeks
7 weeks

Answer 7

almost no changes

coagulation necrosis, edema

coagulation necrosis, pallor

total coagulation necrosis

macrophage resorption of dead myofibers, weakest time period

replacement by granulation tissue

scarring completed

Question 8

complications of MI?

Answer 8

contractile dysfunction
arrhythmias
myocardial rupture
pericarditis
mural thrombus

Question 9

this is a natural death from cardiac causes that fulfills 2 criteria:

2 parts

Answer 9

abrupt loss of consciousness

occurring within 1 hour of the onset of acute symptoms

Question 10

major risk factors of coronary artery atherosclerosis?

Answer 10

hypercholesterolemia
cigarette smoking
hypertension
diabetes mellitus

Question 11

two types of IHD?

Answer 11

acute ischemic heart disease

chronic ischemia heart disease