Integumentary System: anna copy Flashcards
(55 cards)
Skin Functions
-Protection
-Sensation
-Temperature regulation
-Absorption
-Vitamin D production: Calcium absorption, bone strength, muscle, neural, immune function
What type of tissue is epidermis
Keratinized stratified squamous epithelium
What type of tissue is Dermis
Dense irregular CT
Epidermal layers
Stratum basale
Stratum spinosum
Stratum granulosum
Stratum lucidum
Stratum corneum
Bad sons give lame cock
Stratum Basale
Deepest layer
Single layer of “basal cells” (epidermal stem cells)
-Rapidly reproducing cells
-Layer of epidermal regeneration
-Pushed superficially into stratum spinosum
Stratum Spinosum
-“Spiny layer”
-About 10 layers of keratinocytes
-Begin filling with keratin: Trauma-resistant protein
-Attached by desmosomes
-Membrane linker proteins
-Contribute to protective function of skin
Stratum Granulosum
-“Grainy layer”
-About 5 layers of keratinocytes
-Continue to fill with keratin
-Nucleus and organelles destroyed
-Cells flatten
-Produce granules of keratohyalin
-Crosslinks the keratin proteins to
strengthen barrier
Stratum Lucidum
-“Translucent layer”
-Several layers of dead cells
-Packed with eleidin
-Lipid-rich form of keratohyalin
-Waterproof layer
-Found only in “thick skin”
-Typically palms, soles, digits
-“Callus”
Stratum Corneum
-“Horny layer”
-About 30 layers of dead cells
-Flakes of keratin
-Continually sloughing off
-Dry, thick surface protects against
abrasion and infection
Melanocytes
-Found in stratum basale
-Produce melanin
-Protect against UV rays
Merkel Cells
“Tactile cells”
-Respond to light touch
-Release chemicals to stimulate neuron
-Found in stratum basale
Dendritic Cells
“Langerhans cells”
-Immune cells of the skin
-Destroy pathogens that have entered through epidermal abrasions
Nevus
pigmented skin lesion formed from a cluster of melanocytes; “mole”
Freckles
areas of increased melanocyte activity
Hemangiomas
skin discoloration due to abnormal proliferation of blood vessels; “birthmark”
Friction ridges
“epidermal ridges”; cause fingerprints
Dermis
-Deep to the epidermis
-Composed of CT
-Papillary and reticular layers
Papillary Layer
Top layer of dermis
-Loose areolar CT
-Dense capillary network
-Supplies nutrients to deep layers of
epidermis
-Temperature regulation
-Dermal papillae
-Epidermal ridges -> Fingerprints
Reticular Layer
Deep layer of dermis
-Dense irregular CT
-Accessory structures: Hair, Glands, Sensory receptors
Bulb
base of follicle
Papilla: capillary bed
Matrix: living cells divide to form hair
Root
hair from bulb to surface
Follicle
tube surrounding root
Arrector pili muscle
goosebumps
Alopecia
Autoimmune disorder where hair follicles are attacked