Introduction to Parasites Flashcards

1
Q

What is a parasite?

A

An organism that lives in another and gets its food at the expense of the host

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2
Q

What parasitic disease causes the most deaths globally?

A

Malaria

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3
Q

What are the 3 classification of parasites?

A
  • Protozoa
  • Helminths
  • Arthropods
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4
Q

What are protozoa?

A
  • Microscopic, unicellular organisms

- Can be free-living or parasitic in nature

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5
Q

How are protozoa transmitted?

A
  • Protozoa that live in human’s intestines= fecal-oral route

- Protozoa that live in blood/tissue=arthropod route

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6
Q

What kind of infection is malaria?

A

Protozoan

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7
Q

Describe malaria.

A
  • Mosquito-borne disease caused by a parasite
  • Patient often experiences fever, chills and flu like symptoms
  • Left untreated they may develop sever complications and die
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8
Q

What is the name of the parasite involved in malaria?

A

Plasmodium spp

P. falciparum has the highest mortality rate

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9
Q

How is malaria diagnosed/

A

-Giesma stained blood fil shows infected red cells
-Thick and thin blood films
Variety of rapid diagnostic testing

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10
Q

Describe the life cycle of plasmodium spp.

A
  • Sporozoites are injected under the skin
  • They travel through th blood and enter the liver
  • They mature in the liver and re-enter circulation as merozoites
  • They invade RBC, multiply and lyse cells
  • Sexual form is then taken up by mosquito
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11
Q

How can the spread of malaria be controlled?

A
  • Insecticide treated mosquito nets
  • Prophylaxis
  • Malaria vaccine currently being researched
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12
Q

What kind of infection is amoebic dysentery?

A

Protozoal

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13
Q

What causes amoebic dysentery?

A

Entamoeba histolytica

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14
Q

What are the clinical signs of amoebic dysentery?

A
  • Diarrhoea with blood/pus
  • Intestinal and extra intestinal infections
  • Liver abscess in late disease
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15
Q

What would be found on microscopy of amoebic dysentery?

A

Cysts in formed stool

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16
Q

What do trophozoites do in amoebic dysentery?

A

Ingest red cells by throwing out pseudopodia

17
Q

What are nematodes?

A

Roundworms

18
Q

What are cestodes?

19
Q

What are trematodes?

20
Q

How is enterobiasis diagnosed?

Nematode

A
  • Press adhesive sellotape against perianal region in the morning
  • Ova seen on microscopy
21
Q

Describe Ascaris lumbricoides.

A
  • Nematode
  • Ingested eggs hatch in the intestine
  • Larvae carried by circulation to lungs
  • Swallowed again
  • Adult worms develop in and inhabit small intestine
  • Ova seen in faeces by microscopy
22
Q

What symptoms are usually seen with Ascrais lumbricoides?

A
  • Often asymptomatic
  • Transient pulmonary symptoms in Loefler’s syndrome
  • Mass of worms may obstruct small intestine or common bile duct
23
Q

What are 2 examples of cestodes?

A
  • Taenia saginata (beef)

- Taenia solium (pork)

24
Q

What are the hosts in the Taenia spp?

A
  • Larval cysts ingested in meat (intermediate host)

- Adult tapeworm in human (definitive host)

25
How is the taenia spp diagnosed?
- Tissue cysts in humans infected with T solium- cysticercosis - Ova in stools on microscopy
26
What is Echinococcus sp carried by? | Trematode
Dogs, wolves and foxes
27
Describe the life cycle of Ecjinococcus.
- Humans ingest eggs (dog faeces) - Eggs hatch and enter circulation - Hydatid cysts forms in liver - Surgical resection must involve whole cyst
28
What is serology?
Detection of antibodies
29
What diagnostic principles apply to parasitology?
- Culturing is rarely possible - Blood films (thick/thin) for malaria - Serology - Identification of parasites in host tossue or excreta - Microscopy ate P,C and O in faeces
30
What is helminth infection often accompanied by?
- Eosinophilia | - Elevate IgE
31
What can Schistosoma haematobium cause?
- Haematuria | - Bladder cancer
32
What are the 3 major species of Schistosomes?
- S. haematobium (bladder) - S. mansoni (intestinal) - S. japonicum (intestinal)
33
Describe infection of schistosomiasis.
-Eggs excreted in urine or faeces -Miracidia released in fresh water -Penetrate body of snail (intermediate host) -Cercaria emerge from snails after 4-6 weeks Penetrate human skin -Migrate through lungs to liver -Mature in liver into worms that migrate to mesenteric or bladder venules -Lay eggs that cause inflammation in bladder or intestinal wall Katayma fever- acute febrile episode
34
What kind of parasite causes schistosomiasis?
Trematode