Flashcards in Introduction to Viruses Deck (14):
-What 3 structures can viruses take?
-icosahedral( 20 faces, each of which is an equilateral triangle)
-Helical (protein binds around DNA/RNA in a helical fashion
-Complex (neither icosahedral or helical)
What is meant by viruses being obligate intracellular pathogens?
Can only replicate inside host cell
What is meant by tissue tropism?
most viruses have a specific host range and only infect specific host cell types
How can virus families be classified? (4)
-presence/absence of envelope
-mode of replication
What structures make up a virion? (5)
-virion associated polymerase
What steps are involved in virus replication? (7)
-replication of genomic nucleic acid
-budding and release
How can viruses be transmitted? (9)
What is the host range for smallpox and measles?
only infect humans
What can coinfection of human and animal/bird strain in one organism lead to?
recombination and generation of a new strain
What are 4 consequences of viral infection?
-clearance of virus (with no,short or long term immunity)
-transformation (long term infection with altered cellular gene expression)
What kind of immunity is involved in hepatitis C?
no lasting immunity
What kind of immunity is involved in measles?
long term immunity
Give 3 examples of chronic infections