Flashcards in Introduction to Fungi Deck (26):
What can fungi infect?
What is mycology?
The study of fungi
What is a fungi?
A chemo-organotropic eukaryote that lacks chlorophyll and forms spores. Its cell wall contains polysaccharides, often, chitin or glucan and it absorbs nutrients. Its membrane contains egosterol as the major sterol.
What are the 3 groups of fungi?
What are the sexual and asexual spores of each group?
What are examples of ascomycetes?
What is an example o of a basidiomycete?
What is an example of a zygomycete/
What are yeasts?
Fungi that favour a unicellular habit
What non-fatal diseases can fungi cause?
-Athletes foot: Epidermophyton, Microsporum and Trichophyton spp
Pityriasis veriscolor: Malssezia spp
What are ringworm infections usually called?
What is dermatophytosis caused by?
Moulds with a dredilection to degrade keratin as a nutrient source
What are the causative agents of dermatophytosis?
What is the causative agent of pityriasis veriscolor?
What is pityriasis veriscolor caused by?
Yeasts that also form hyphae in infected skin
What group of immunocompromised individuals does Candida species affect?
Infect deep organs of patients with various types of immune dysfunction e.g. after abdominal surgery, burns
What group of immunocrompromised individuals does Aspergillus species affect?
Infect deep organs of patients undergoing chemotherapy and stem cell transplantation
What factors contribute to pathogenicity of fungal infections?
-Broad-spectrum antibacterial agents reduce competition for epithelial colonisation sites in gut
What are examples of iatrogenic immunosuppression of host defenced?
What are examples of disease process that can immunosuppress host defenced?
Describe candida specie.
-Commensal to GI tract
-Most infections are enogenous
-Candida spp are yeasts
-C.albicans can form hyphae
What infections can Candida spp cause?
-Superficial of mouth, vagina, penis, skin, nails
-Deep-seated: disseminated infections in seriously immunocompromised hosts
How can chronic mucocutaneous Candida infections arise?
In individuals with an unusual combination of endocrine and immune dysfunction
Describe aspergillus spp.
-Ubiquitous in the environment: infection occurs by spore inhalation
What is invasive pulmonary aspergillosis mainly associated with?