Tumour Pathology 1 Flashcards Preview

Principles of Disease > Tumour Pathology 1 > Flashcards

Flashcards in Tumour Pathology 1 Deck (25):
1

What is a tumour?

-an abnormal growing mass of cells

2

Describe the growth of a tumour.

-Its growth is uncoordinated with that of surrounding normal tissues
--Its growth continues after the removal of any stimulus which may have cause the tumour
-It is an irreversible change

3

What are the 2 types of tumour?

-benign
-malignant

4

What is cancer?

A fundamental property of cancer is its ability to invade into adjacent tissue and to metastasise and grow at other sites of the body.

5

What factors contribute to causation of cancer?

-genetic
-environmental

6

What are the 5 most common types of cancer in males?

-prostate
-lung
-colon
-bladder
-lymph node

7

What are the 5 most common types of cancer in females?

-breast
-lung
-colon
-uterus
-ovary

8

What are the 5 most common types of cancer overall?

-breast
-lung
-prostate
-colon
-melanoma

9

How does 5-year survival rates vary?

-Rates vary greatly
-Melanoma has a 90% survival rate
-Lung only has a 15% survival rate

10

How are tumours classified?

-based on tissue of origin
-benign vs malignant

11

What tissues can cancer originate in?

-epithelium
-connective tissue
-blood
-lymphoid tissue
-neural tissue
-germ cells

12

What are glandular (epithelium) tumours called?

-benign= adenoma
-malignant= adeno-carcinoma

13

What are squamous (epithelium) tumours called?

-benign= squamous papilloma
-malignant= squamous carcinoma

14

What are bone (connective tissue) tumours called?

-benign= osteoma
-malignant= osteo-sarcoma

15

What are fat (connective tissue) tumours called?

-benign=lipoma
-malignant= lipo-sarcoma

16

What are fibrous tissue(connective tissue) tumours called?

-benign= fibroma
-malignant= fibro-sarcoma

17

What are tumours of white blood cells called?

-malignant= leukaemia

18

What are tumours of the lymphoid tissue called?

-malignant= lymphoma

19

What are tumours of the central nervous system called?

astrocytoma

20

what are tumours of the peripheral nervous system called?

Schwannoma

21

What are tumours of germ cells called?

teratomas

22

How do teratomas differ in males and females.

Ovarian teratomas are usually benign whereas testicular teratomas are usually malignant.

23

What is a teratoma composed of?

various tissues

24

What are the features of a benign tumour? (7)

-non-invasive growth pattern
-usually encapsulated
-no evidence of invasion
-no metastases
-cells are similar to normal
-benign tumours are well differentiated
-function similar to normal tissue
-rarely cause death

25

What are the features of a malignant tumour? (7)

-invasive growth pattern
-no capsule or capsule breached by tumour cells
-cells abnormal
-cancer often poorly differentiated
-loss of normal function
-often evidence of spread of cancer
-frequently cause death