Lecture 10 - Intro to ANS Flashcards Preview

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Flashcards in Lecture 10 - Intro to ANS Deck (112)
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1

Describe the ANS.

Unconscious control
Visceral functions

2

Describe the somatic nervous system.

Conscious control
Movement, posture

3

What are all pre-synaptic terminals composed of? (receptor, NT)

ACh to Nicotinic

4

What are all PNS synapses composed of? (receptor, NT)

ACh to Muscarinic

5

What are all NMJ's composed of? (receptor, NT)

ACh to Nicotinic

6

What are three types of SNS receptors?

M + A/B + D

7

Where are SNS M found? What stimulates them?

Sweat glands, ACh

8

Where are SNS A/B receptors found? What stimulates them?

Cardiac + Smooth Muscle
Gland cells + Nerve terminals
NE

9

Where are SNS D receptors found? What stimulates them?

Dopamine
Renal vascular SM

10

Where do PNS preganglionic fibers originate?

Midbrain + Medulla Oblongata + Sacral area

11

Are preganglionic fibers of PNS short or long?

Long

12

Where do preganglionic fibers from SNS synapse?

Paravertrbral chains

13

Where do SNS preganglionic fibers originate?

Thoracic + Lumbar

14

What is special about the SNS in regards to having the paravertberal chain?

Can coordinate reactions

15

What does SNS NE act on?

Alpha + Beta1 receptors

16

What does the epinephrine from adrenal medulla act on receptor wise?

Alpha + Beta

17

List all the places (we need to know) that ACh is released from.

Pre-ganglionic fibers
Post-ganglionic PNS
SNS to sweat glands
Adrenal medulla innervation
NMJ

18

List all the places (we need to know) that NE is released.

Most port-ganglionic SNS
Adrenal medulla

19

What is acetylcholine made from?

Choline + Acetyl CoA

20

What enzyme makes ACh?

ChAT

21

Describe how cholinergic transmission occurs.

Choline enters cell via CHT (w/ Na)
ChAT makes ACh
VAT takes in ACh into vesicle
Stimulus occurs - vesicle is released
ACh broken down via AChE
Choline take back up into nerve terminal

22

Describe how adrenergic transmission occurs.

Tyrosine enters cell (w/ Na)
Tyrosine hydroxylase makes L-DOPA
L-DOPA becomes Dopamine
VMAT take dopamine into the vesicle
Dopamine becomes NE
Stimulus causes NE release
NE taken back into cell via NET

23

What drug inhibits Tyrosine hydroxylase?

Metyrosine

24

What drug depletes NE from vesicle?

Reserpine

25

What drugs inhibit NET?

Cocaine + Antidepressants

26

What drugs inhibit CHT?

Hemicholiniums

27

What drugs inhibit VAT?

Vesamicol

28

What toxin inhibits ACh release?

Botulism

29

What do amphetamines do to adrenergic transmission?

Reverse transport to increase release

30

What two enzymes metabolize NE?

MAO + COMT