Lecture 2 - Epithelial Cells Flashcards Preview

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Flashcards in Lecture 2 - Epithelial Cells Deck (33):
1

Do epithelial cells have blood supply?

No

2

What Is the Basal Lamina?

Lamina Lucida
Lamina Densa

3

What is the basement membrane?

Lamina Densa
Reticular Fibers
Includes Anchoring Fibril (Type VII Collagen)

4

Type IV collagen is made by ______.

Epithelial Cells

5

Type III and VII collagen are made by ______.

Connective Tissue Cells

6

Tight Junction Protein and Function

1. Claudin
2. Helps seal the cell, preventing water loss as well as the passage of substances in between the cells

7

Adherent Junction Protein

Cadherin (interacts in precence of Ca2+) + Catenin + acting-binding protein + actin fillament

8

Adherent Junction Shape and function

Surrounds the Cell, stability, and help seal the tight junction

9

Desmosome Protein

Cadherin + Desmoplakin/Plakoglobin + Intermediate filament

10

Desmosome Shape and Function

Does not encircle, goes through the cell, anchors to intermediate filaments, provides stability to the cell

11

Gap Junction Protein

Connexin
Forms hydrophilic pore

12

Hemidesmosome Protein

Integrin

13

Microvilli Structure

Microfilaments go up into microvilli to give support
- Made of actin + connecting fibers

14

Stereocilia

Longer than microvilli
branched

15

function of stereocilia

facilitate absorption

16

Cilia shape

Longer/wider than microvili

17

cilia function

movement

18

glandular epithelia orgin

from epithelial layer during fetal development

19

glandular epithelia function

secretion

20

goblet cell formation

During fetal development, goblet cells differentiate from epithelial cells

21

Goblet cell function

secrete mucous for intestine and respiratory tracts

22

Goblet cells, single or multicellular gland?

single

23

Endocrine vs Exocrine

Endocrine does not have ducts
Exocrine has ducts

24

Formation of endo/exocrine glands

During fetal development there is a proliferation and differentiation of epithelial cells into ductal and secretory epithelial cells
Do not break BL/BM

25

Different Types of Exocrine Gland Structural classifications (simple x4)

1. Tubular
2. Branched Tubular
3. Acinar
4. Branched Acinar

26

Different Types of Exocrine Gland Structural classifications (compound x3)

1. Tubular
2. Acinar
3. Tubuloacinar

27

Different Types of exocrine glands (x3)

Merocrine
Holocrine
Apocrine

28

Merocrine Secretion

Most Exocrine Glands
Most proteins do not diffuse across the membrane --> use exocytosis

29

Apocrine Secretion

Apical membrane w/ cytoplasm and lipid droplet pinches off
-can produce large quantities --> mammary gland

30

Holocrine Gland

aka sebaceous glands
cells disintegrate and everything goes into ducts
-think "pimple"

31

Synonym for tight junctions

Zonulae Occuldens

32

Synonym for adherent junctions

Zonula Adherens

33

Synonym for desmosome

Macula Adherens