Lecture 2 - Epithelial Cells Flashcards

1
Q

Do epithelial cells have blood supply?

A

No

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2
Q

What Is the Basal Lamina?

A

Lamina Lucida

Lamina Densa

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3
Q

What is the basement membrane?

A

Lamina Densa
Reticular Fibers
Includes Anchoring Fibril (Type VII Collagen)

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4
Q

Type IV collagen is made by ______.

A

Epithelial Cells

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5
Q

Type III and VII collagen are made by ______.

A

Connective Tissue Cells

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6
Q

Tight Junction Protein and Function

A
  1. Claudin

2. Helps seal the cell, preventing water loss as well as the passage of substances in between the cells

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7
Q

Adherent Junction Protein

A

Cadherin (interacts in precence of Ca2+) + Catenin + acting-binding protein + actin fillament

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8
Q

Adherent Junction Shape and function

A

Surrounds the Cell, stability, and help seal the tight junction

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9
Q

Desmosome Protein

A

Cadherin + Desmoplakin/Plakoglobin + Intermediate filament

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10
Q

Desmosome Shape and Function

A

Does not encircle, goes through the cell, anchors to intermediate filaments, provides stability to the cell

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11
Q

Gap Junction Protein

A

Connexin

Forms hydrophilic pore

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12
Q

Hemidesmosome Protein

A

Integrin

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13
Q

Microvilli Structure

A

Microfilaments go up into microvilli to give support

- Made of actin + connecting fibers

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14
Q

Stereocilia

A

Longer than microvilli

branched

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15
Q

function of stereocilia

A

facilitate absorption

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16
Q

Cilia shape

A

Longer/wider than microvili

17
Q

cilia function

18
Q

glandular epithelia orgin

A

from epithelial layer during fetal development

19
Q

glandular epithelia function

20
Q

goblet cell formation

A

During fetal development, goblet cells differentiate from epithelial cells

21
Q

Goblet cell function

A

secrete mucous for intestine and respiratory tracts

22
Q

Goblet cells, single or multicellular gland?

23
Q

Endocrine vs Exocrine

A

Endocrine does not have ducts

Exocrine has ducts

24
Q

Formation of endo/exocrine glands

A

During fetal development there is a proliferation and differentiation of epithelial cells into ductal and secretory epithelial cells
Do not break BL/BM

25
Different Types of Exocrine Gland Structural classifications (simple x4)
1. Tubular 2. Branched Tubular 3. Acinar 4. Branched Acinar
26
Different Types of Exocrine Gland Structural classifications (compound x3)
1. Tubular 2. Acinar 3. Tubuloacinar
27
Different Types of exocrine glands (x3)
Merocrine Holocrine Apocrine
28
Merocrine Secretion
Most Exocrine Glands | Most proteins do not diffuse across the membrane --> use exocytosis
29
Apocrine Secretion
Apical membrane w/ cytoplasm and lipid droplet pinches off | -can produce large quantities --> mammary gland
30
Holocrine Gland
aka sebaceous glands cells disintegrate and everything goes into ducts -think "pimple"
31
Synonym for tight junctions
Zonulae Occuldens
32
Synonym for adherent junctions
Zonula Adherens
33
Synonym for desmosome
Macula Adherens