Lecture 22: The Small Intestine Flashcards

1
Q

What are the 3 main regions of the small intestine?

A
  • Duodenum
  • Jejunum
  • Ileum
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2
Q

What is the total length of the small intestine?

A

6m

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3
Q

Where is the initial segment of the duodenum?

A

Retroperitoneal

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4
Q

What is the small intestine held in place by?

A

The Mesentery

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5
Q

What does the Mesentery allow?

A

Allows movement but prevents the SI from getting tangled

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6
Q

What does the Mesentery contain?

4

A
  • Arteries
  • Veins
  • Nerves
  • Lymphatics
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7
Q

What is a property of the chyme received by the SI?

A

Acidic

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8
Q

What protects the epithelium in the SI?

2

A
  • Mucous secreting cells

- Glands in the submucosa

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9
Q

What is the only section of the SI to contain glands in its submucosa?

A

Duodenum

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10
Q

What neutralises the acidic chyme in the SI?

A

Bicarbonate

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11
Q

Where is bicarbonate produced to neutralise chyme?

A

Pancreas

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12
Q

What are Plicae Circulares (Circular folds)?

A

Permanent large folds of the small intestine

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13
Q

What is the core of the Place Circulares made of?

A

Submucosa with overlying mucosa

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14
Q

What is found on the Plicae circulares?

A

Numerous villi

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15
Q

What does the Muscularis mucosae allow the villi to do?

A

Allow them to wiggle back and forth

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16
Q

What is the core of the Villi made from?

A

Fibrous Connective Tissue (lamina propria)

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17
Q

What do the Villi contain?

2

A
  • Lymph lacteal

- Capillary network

18
Q

What does the lymph lacteal drain?

A

Products of fat digestion

19
Q

What does the capillary network drain?

A

Products of protein and carbohydrate digestion

20
Q

What does nutrient rich deoxygenated blood in the small intestine enter?

A

The mesenteric veins

21
Q

What do the mesenteric veins drain into?

A

Hepatic portal vein

22
Q

What pathway do lymph lacteals ultimately drain into?

A

Into the Cisterna Chyli, thoracic duct and then left subclavian vein

23
Q

What do mesentery do?

A

Connect organ to body wall

24
Q

What is the epithelium of the SI?

A

Simple columnar

25
What is on the apical surface of the SI epithelium?
Microvilli
26
What is the role of the microvilli?
Increase the surface area
27
Where are Gycocalyx?
In the microvilli brush border
28
What is the Gycocalyx made of? | 2
- Glycoproteins | - Branched filaments
29
What is the function of the Gycocalyx?
Tether enzymes
30
What does contact digestion involve?
Enzymes attached to the brush border
31
What is the plasma membrane?
A selectively permeable membrane
32
What is contained in the plasma membrane? | 3
- Proteins - Channels - Transporters
33
What holds epithelial cells together?
Tight junctions
34
What can diffuse through tight junctions?
Small molecules
35
What cells are in the epithelium of the small intestine? | 5
- Enterocytes - Goblet cells - Stem cells - Paneth cells - Endocrine cells
36
What do enterocytes do?
Absorptive cells
37
What do goblet cells do?
Secret mucous for protection
38
What do stem cells do?
Make all cell types
39
What do Paneth cells do?
Secrete granules, antibacterial enzymes
40
What do Endocrine cells do?
Secrete hormones