Memory Disorders Flashcards Preview

MD1 Neuroscience > Memory Disorders > Flashcards

Flashcards in Memory Disorders Deck (37):
1

Does subject complaint predict memory performance?

Not necessarily, but may pre-date formal deficits in some cases of dementia

2

Define memory

Processes used to acquire, store, retain, and retrieve information

3

What often accompanies profound anterograde amnesia?

Retrograde amnesia; eg: post traumatic amnesia

4

What is short-term memory?

Immediate memory

5

What is working memory?

Manipulation of immediate memory

6

How can immediate memory be measured?

Digit span

7

What is long-term memory?

Storing info over mins, hrs, years for later retrieval

8

How can long-term memory be measured?

List learning retrieval

9

What type of memory does anterograde amnesia affect: short-term or long-term?

Long-term

10

What are the types of declarative memory?

Episodic
Semantic

11

What are the types of non-declarative memory?

Skills and habits
Classical conditioning

12

What is procedural memory?

Long-term, implicit memory
Skill acquisition

13

What type of memory often breaks down: declarative or non-declarative?

Declarative

14

What is episodic memory?

Autobiographical - events in personal context

15

What is semantic memory?

General facts not specified to individual
Not contextual

16

What is the structure of declarative memory?

Hippocampus
Entorhinal cortex
Perirhinal cortex

17

What is the entorhinal cortex?

Gateway into hippocampus

18

Where does disease progression affecting declarative memory often start?

Entorhinal cortex

19

What does the perirhinal cortex do?

Linked to object knowledge and recognition

20

What does the parahippocampal region do?

Involved in spatial memory

21

What does damage to the parahippocampal region cause?

Getting lost

22

What does damage to different parts of the hippocampus cause?

Slightly different presentations of memory loss

23

What is the dentate gyrus on the hippocampus responsible for?

Pattern recognition

24

What is CA1 in the hippocampus very susceptible to?

Hypoxic injury

25

What is the left hippocampus more lateralised to do?

Verbal memory
- List learning
- Paired associate learning
- Story recall

26

What is the right hippocampus more lateralised to do?

Non-verbal memory
- Visuo-spatial associations
- Face recall

27

What are some causes of memory impairment?

Degenerative disorders
Cerebrovascular disorders
Paroxysmal/transient disorders
Surgical resection

28

What are the episodic memory structures in the midline?

Anterior thalamus
Basal forebrain
Mesial temporal region
Mammillary bodies
Retrosplenial cortex

29

What is transient global amnesia?

Anterograde amnesia for

30

What precipitates transient global amnesia?

Several, including
- Sexual intercourse
- Immersion in cold water
- Emotional stress

31

Is there a disruption to self-identity in transient global amnesia?

No

32

What is the underlying cause of transient global amnesia?

Unknown

33

What is the most common cause of dementia?

Alzheimer's disease

34

When does Alzheimer's disease usually start?

Over 65

35

What is mild cognitive impairment?

Subclinical
Transition phase between normal ageing and dementia

36

What are the clinical signs of mild cognitive impairment?

Self-reported memory complaint
Objective memory impairment
Unaffected general cognitive functioning
Normal capacity to perform activities of daily living

37

What are early memory complaints in mild cognitive impairments?

Name-face association: "What's his name?"
Object-place association: "Where did I leave my glasses?"

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