Neonatal Meningitis E.coli (NMEC) Flashcards
1
Q
A
2
Q
what is the biology of Neonatal Meningitis K1 E. coli?
A
- Gram Negative Bacilli
- Lactose Fermenter
- Encapsulated K-1
3
Q
where is Neonatal Meningitis K1 E. coli normal in the body?
A
in the colon
4
Q
how does Neonatal Meningitis K1 E. coli get transmitted to neonate?
A
vaginal delivery where neonate gets exposed to colonic flora of mother
5
Q
a neonate infected with NMEC will present with what?
A
Meningitis (High fever, vomiting, irritability lethargy, bulging fontanelle)
6
Q
what structure will protect NMEC from complement and opsonization, thus it will gain access to the CNS?
A
a capsule
7
Q
how is diagnosis of NMEC confirmed?
what will be seen?
A
Gram stain of CSF
CSF -> Cloudy, PMNs, low glucose, high protein
8
Q
what is the treatment of NMEC?
A
Cephalosporin -Ceftrixone
9
Q
A
