Klebsiella pneumoniae Flashcards Preview

Microbiology Block 3 > Klebsiella pneumoniae > Flashcards

Flashcards in Klebsiella pneumoniae Deck (15):
1

what is the biology of klebsiella pneumoniae?

  • Gram Negative Bacilli
  • Lactose Fermenter-Purple Mucoid
  • Encapsulated

2

where is klebsiella penumoniae normally found?

in the colon

3

how is klebsiella pneumoniae acquired nosocomially?

ventilators

4

who is most prone to acquiring klebsiella pneumoniae?

alchoholics

5

what protects klebsiella penumoniae from complement and opsonization, thus gains access to CNS?

the capsule

6

infection with klebsiella penumoniae will present with what clincally?

  • UTI/Cystitis 
  • Pneumonia esp. D-VAP*
  • Meningitis

7

how do you treat an infection with klebsiella penumoniae?

3rd Generation Cephalosporin

8

what resistance can klebsiella pneumoniae develop that makes it a major health threat?

Carbepenem-Resistance (CRKP)

9

what is the major virulence factor in the Klebsiella pneumoniae bacteria?

the capsule

10

how does klebsiella pneumoniae look like in MacConkey agar?

Purple-pink mucoid-colonies

A image thumb
11

what is an important clue to determining community-acquired klebsiella pneumoniae?

“Current grape jelly” purple viscous sputum

12

what is a clue to determining Nosocomial Ventilator-Associated Pneumonia (VAP)?

Delayed* presentation (~5-7 days after ventilator)

13

what is so bad about Carbepenase-Resistant Klebsiella (CRKP)?

it is multiple drug resistant

14

what is Plasmid-encoded carbapenase, found in carbepenemase-resistant klebsiella pneumoniae?

is a B-lactamase that degrades all B-lactams

15