Haemophilus Flashcards Preview

Microbiology Block 3 > Haemophilus > Flashcards

Flashcards in Haemophilus Deck (27):
1

what is the biology of heamophilus?

Pleomorphic GNB * 

 

2

what are the Medically imp. species of haemophilus?

  • Haemophilus influenzae *
  • H. ducreyi
  • H. aegypticus

3

apart from pleomorphic, haemophilus can as well be identified other times in what shape?

coccobacilli

4

fastidious haemophilus influenzae has 2 important factors?

Hemin (factor X) and NAD (factor V) *

 

5

what agar is used to identify haemophilus influenzae?

chocolate blood agar

6

where is haemophilus influenzae found normally in the body?

nasopharynx

7

what strains of haemphilus are more virulent?

encapsulated strains

8

how does haemophilus influenzae spread?

respiratory droplets

9

what is the 2nd encapsulated strain of haemophilus influenzae?

Type b 

 

10

what is the type B capsule made of?

 polyribitol phosphate (PRP) *

11

what test used to diagnose type B haemophilus influenzae?

CSF antigen screens *

12

haemophilus influenza capsule is used for what purpose medically?

vaccination

13

does H. influenzae have IgA protease *? what does it do?

yes; Degrades secretory IgA facilitating colonization of upper respiratory mucosa

14

Colonization of upper respiratory mucosa may lead to continous spread causing what?

  • Sinusitis, otitis media 
  • Epiglottitis 
  • Bronchopneumonia

15

if h. influenzae becomes bacterimic, it will lead to what?

  • Meningitis 
  • Septic arthritis

16

what diseases does Haemophilus influenzae cause?

  • Otitis media , Sinusitis *
  • Bronchitis, Pneumonia * (NTHi)
  • Meningitis *
  • Epiglottitis * - Life-threatening emergency 
  • Cellulitis
  • Septic arthritis

 

17

who is susceptible to meningitis due to h. influenzae?

unvaccinated children (3 months to 2 years)

18

what is a good way to confirm a meningitis diagnosis due to h. influenzae?

CSF gram stain * – showing gram negative coccobacilli

 

19

20

what is the treatment for meningitis due to h. influenzae?

Ceftriaxone

21

what is the treatment for sinusitis due to h. influenzae?

ampicillin

22

what is the treatment for otitis media due to h. influenzae?

ampicillin

23

what two other haemophilus species are there?

H. aegyptius *

H. ducreyi *

 

24

what does H. aegyptius * cause?

purulent conjunctivitis, “pink eye”

25

what does H. ducreyi * cause?

Genital ulcers – “Chancroid”, an STD *

  • Soft, painful ulcer
  • Open lesions increase transmission of HIV

26

H. ducreyi caused genital ulcers are treated with what?

erythromycin

27

how does H. ducreyi spread?

sexually transmitted