Enteric Gram Negative Bacilli (GNB)

Question 1

all enterobacterie have what protein in their cell wall?

Answer 1

lipopolysachiride

Question 2

lipopolysacharide has what type of toxin? what is another name for it?

Answer 2

endotoxin = toxin A

Question 3

enterobacter disease symptoms result form what?

Answer 3

host-mediated damage.

Question 4

Lipid-A of LPS binds to what on host cells?

Answer 4

TLR4/CD14 on host cells

Question 5

Macrophages produce pro-inflammatory cytokines, which one in excess may lead to septic shock?

Answer 5

Too much TNF α

Question 6

What mechanism is used to directly inject effector molecules into host cell?

Answer 6

Type 3 Secretion System T3SS

Question 7

Serotyping enteric gram - bacteria can be against what structures of th bacteria?

Answer 7

Flagella (H)

Capsule (V or K)

LPS sugar residue (O)

Question 8

what kind of feature is a flagella to Enterobacteriacease?

Answer 8

variable

Question 9

Motility (flagella) is a critical virulence factor for Gram Negative why?

Answer 9

to navigate water/food intermediate and to penetrate mucus layer.

Question 10

Type 3 Secretion System T3SS is what kind of feature on all Enterobacteriaceae?

Answer 10

Common Feature

Question 11

what treatment is used for enterobacterie?

Answer 11

Symptom management OR Ciprofloxacin if systemic