Flashcards in UroPathogenic E.coli (UPEC) Deck (11):
1
what is the biology of UPEC?
- Gram Negative Bacilli
- Lactose Fermenter
- Reduce Nitrate to Nitrite
2
how is the course of the pathogenesis of UPEC?
Fimbriae attaches to uro-epithelial cells and biofilm is formed.
3
what will cause the Pyogenic symptoms seen in UPEC?
are mediated by hemolysin and immune response to LPS
4
where is UPEC flora normal in the body?
colon
5
how is UPEC infection get acquired in hospitals?
through catheters
6
how is UPEC infection get acquired in the community?
lack of hygiene
7
how will an infection with UPEC present with?
- UTI/Cystitis (90% of cases)
- Low grade fever, dysuria
- Pyelonephritis
- high fever, dysuria, low flank pain
8
how is an infection with UPEC diagnosed?
Urinalysis
9
how do you treat UPEC?
*TMP-SMX
*Fluoroquinolones
*Based on urinalysis Ab-R/S
10
what will a UTI Urinalysis detect?
Nitrites
11