ORGANOTROPIC AGENTS - Antihypertensive drugs Flashcards Preview

Pharmacology > ORGANOTROPIC AGENTS - Antihypertensive drugs > Flashcards

Flashcards in ORGANOTROPIC AGENTS - Antihypertensive drugs Deck (39):
1

This drug reduces blood pressure by acting on vasomotor centers in the CNS

Clonidine

2

The following are central acting antihypertensive drugs

- Methyldopa
- Clonidine
- Moxonidine

3

A ganglioblocking drug for hypertension treatment is

Trimethaphan

4

A sympatholythic drug

Guanethidine

5

Drug with nonselective beta-adrenoblocking activity

Propranolol

6

The selective blocker of beta-1 adrenoreceptors

Atenolol

7

An alpha and beta adrenoreceptors blocker

Labetalol

8

This drug inhibits the angiotensin-converting enzyme

- Captopril
- Enalapril
- Ramipril

9

This drug is a directly acting vasodilator

Nifedipine

10

Diuretic agent for hypertension treatment

Dichlothiazide

11

This drug blocks alpha-1 adrenergic receptors

Prazosin

12

This drug activates alpha-2 adrenergic receptors

Clonidine

13

This drug is an inhibitor of renin synthesis

Propranolol

14

This drug is a non-peptide angiotensin II receptor antagonist

Losartan

15

This drug is a potassium channel activator

Diazoxide

16

True or False about angiotensin II. It is a peptide hormone

TRUE

17

True or False about angiotensin II. It stimulates the secretion of aldosterone

TRUE

18

True or False about angiotensin II. Angiotensin I is almost as potent as angiotensin II

FALSE

19

True or False about angiotensin II. It is a potent vasoconstrictor

TRUE

20

This drug is contraindicated in patients with bronchial asthma

Propranolol

21

This drug is converted to an active metabolite after absorption

Enalapril

22

This drug routinely produces some tachycardia

Nifedipine

23

True or False about vasodilators. Hydralazine causes tachycardia

TRUE

24

True or False about vasodilators. Nifedipine is a dopamine receptor antagonist

FALSE

25

True or False about vasodilators. Nitroprusside dilates both arterioles and veins

TRUE

26

True or False about vasodilators. Minoxidil can cause hypertrichosis

TRUE

27

True or False about verapamil. It blocks L-type calcium channels

TRUE

28

True or False about verapamil. It increases heart rate

FALSE

29

True or False about verapamil. It relaxes coronary artery smooth muscle

TRUE

30

True or False about verapamil. It depresses cardiac contractility

TRUE

31

Unwanted effects of clonidine

Sedative and hypnotic effects

32

The reason of beta-blockers administration for hypertension treatment is

Decreasing of heart work

33

An endogenous vasoconstrictor that can stimulate aldosterone release from suprarenal glands

Angiotensin II

34

The group of antihypertensive drugs which diminishes the metabolism of bradykinin

Angiotensin-converting enzyme inhibitors

35

Hydralazine (a vasodilator) can produce

Tachycardia, lupus erhythromatosis

36

Vasodilator which releases NO

Sodium nitroprusside

37

The reason of diuretics administration for hypertension treatment is

Diminishing of blood volume and amount of Na+ ions in the vessels endothelium

38

Diuretic agent – aldosterone antagonist

Spironolactone

39

Diuretic agent having a potent and rapid effect

Furosemide

Decks in Pharmacology Class (41):