AGENTS, CONTROLLING THE FUNCTIONS OF THE CENTRAL NERVOUS SYSTEM - Non-narcotic analgesics Flashcards

1
Q

Non-narcotic analgesics are mainly effective against pain associated with

A

Inflammation or tissue damage

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2
Q

Non-narcotic agents cause

A

Antipyretic effect

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3
Q

Non-narcotic analgesics are

A
  • Paracetamol
  • Acetylsalicylic acid
  • Ketorolac
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4
Q

Non-narcotic analgesics are not

A

Butorphanol

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5
Q

Select the non-narcotic drug, which is a paraaminophenol derivative

A

Paracetamol

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6
Q

Which of the following non-narcotic agents is salicylic acid derivative?

A

Aspirin

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7
Q

Tick pirazolone derivative

A

Analgin

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8
Q

Which non-narcotic agents inhibits mainly cyclooxygenase (COX) in CNS?

A

Paracetamol

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9
Q

Most of non-narcotic analgetics have

A
  • Anti-inflammatory effect
  • Analgesic effect
  • Antipyretic effect
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10
Q

Indicate the non-narcotic analgesic, which lacks an anti-inflammatory effect

A

Paracetamol

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11
Q

True or False about aspirin. It inhibits mainly peripheral COX

A

TRUE

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12
Q

True or False about aspirin. It does not have an anti-inflammatory effect

A

FALSE

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13
Q

True or False about aspirin. It inhibits platelet aggregation.

A

TRUE

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14
Q

True or False about aspirin. It stimulates respiration by a direct action on the respiratory center

A

TRUE

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15
Q

For which conditions could aspirin be used prophylactically?

A

Thromboembolism

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16
Q

All of the following are undesirable effects of aspirin

A
  • Gastritis with focal erosions
  • Bleeding due to a decrease of platelet aggregation
  • Reversible renal insufficiency
17
Q

Is not a Undesirable effects of aspirin

A

Tolerance and physical addiction

18
Q

Characteristic findinds of salicylism include

A
  • Headache, mental confusion and drowsiness
  • Tinnitus and difficulty in hearing
  • Hyperthermia, sweating, thirst, hyperventilation, vomiting and diarrhea
19
Q

Analgin usefulness is limited by

A

Agranulocytosis

20
Q

Methemoglobinemia is possible adverse effect of

A

Paracetamol

21
Q

True or False for ketorolac. It inhibits COX

22
Q

True or False for ketorolac. It is as effective as morphine for a short-term relief from moderate to severe pain

23
Q

True or False for ketorolac. It has a high potential for physical dependence and abuse

24
Q

True or False for ketorolac. It does not produce respiratory depression

25
Indicate the nonopioid agent of central effect with analgesic activity
Clopheline
26
Select the antiseizure drug with an analgesic component of effect
Carbamazepine
27
Which nonopioid agents is an antidepressant with analgesic activity?
Amitriptyline
28
Tick mixed (opioid/non-opioid) agent
Tramadol